An interventional study of High fiber sugar free biscuit in Impaired Glucose Tolerance, sponsored by China Medical University Hospital. Status unknown at 1 site in Taiwan. Open to female participants aged 30 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-04-07.
Sponsored by China Medical University Hospital · Not applicable, Interventional, and Prevention
The increase in diabetic population of the world is among the top ten causes of death; with diabetes always high on the list of causes of death. Diabetes is always relative to other major causes of death, (e.g. in cerebral vascular disease, cardiovascular disease and renal disease).
The eating habits and patterns of the diabetic patient are the main causes for poor glycemic control. In epidemiological studies, high fiber and low sugar dietary intake can significantly reduce the incidence of diabetes.
The purpose of this study is to investigate the effect of high fiber sugar-free biscuits in regulating blood glucose in pre-diabetic subjects.
The study will be conducted in three periods:
Period-I:
The recruitment of 60 pre-diabetic subjects:
Subjects of blood glucose levels "Impaired fasting glucose; IFG": fasting blood glucose ≧ 100 mg / dL, \< 126 mg / dL or "Impaired glucose tolerance; IGT": 2 hours postprandial blood glucose ≧ 140mg/dL, \< 200 mg/dL or clinically judged to be mild or moderate diabetes mellitus (HbA1c \< 9%).
In addition to perform pre-test, all subjects also need to complete nutrition counseling and nutrition education .
All 60 subjects are randomly selected into two groups, Group-1,30 subjects, (Placebo group, normal fiber and normal sugar biscuit group), Group-2, 30 subjects, (Experimental group, high fiber and sugar free biscuit group)
The period-II:
Duration: 8 weeks Group-1,30 subjects, (Placebo group, normal fiber and normal sugar biscuit group) , All 30 subjects consume 3 servings of Low-fiber, normal sugar biscuits daily.
Group-2, 30 subjects, (Experimental group, high fiber and sugar free biscuit group) All 30 subjects consume 3 serving of high-fiber, and sugar free biscuits (containing 16 grams of fiber) daily.
Post-period:
Blood samples of all 60 subjects will be collected to compare with period-I and period-II at the first day of 9th week.
Report of expectation:
The purpose of this study is to help the pre-diabetic subjects to reduce the risk of becoming diabetic through the consuming of high fiber and sugar free biscuits and nutrition education.
The increase in diabetic population of the world, is among the top ten causes of death; with diabetes always a top cause of death. Diabetes is always related with other major causes of death, (e.g. in cerebral vascular disease, cardiovascular disease and renal disease).
The eating habits and patterns of diabetic patient are the main causes for poor glycemic control. In epidemiological studies, high fiber rand low sugar dietary intake can significantly reduce the incidence of diabetes.
The purpose of this study is to investigate the effect of high fiber sugar-free biscuits in regulating blood glucose in pre-diabetic subjects.
The study will be conducted in three periods:
Period-I:
The recruitment of 60 pre-diabetic subjects:
Subjects of blood glucose levels "Impaired fasting glucose; IFG": fasting blood glucose ≧ 100 mg / dL, \< 126 mg/dL or "Impaired glucose tolerance; IGT": 2 hours postprandial blood glucose ≧ 140mg/dL, \< 200 mg/dL or clinically judged to be mild or moderate diabetes mellitus (HbA1c \< 9%) .
In addition to perform pre-test, all subjects also need to complete nutrition counseling and nutrition education .
All 60 subjects are randomly selected into two groups, Group-1,30 subjects, (Placebo group, normal fiber and normal sugar biscuit group) , Group-2, 30 subjects, (Experimental group, high fiber and sugar free biscuit group)
Blood samples will be collected from all 60 subjects to investigate:
HbA1c, Blood sugars(Fasting and 2 hours after meal), Insulin, Fructosamine, SGOT,SGPT,ALK-P,TOTAL PROTEIN, Albumin, Globulin, Ketone, Bun,Creatinine, Cholesterol,TG,LDl,HDL, WBC,RBC,Hgb,Hct,M.C.V.,MCH,MCHC,Platelet.
The period-II:
Duration: 8 weeks Group-1,30 subjects, (Placebo group, normal fiber and normal sugar biscuit group), All 30 subjects consume 3 serving of Low-fiber, normal sugar biscuits daily.
Group-2, 30 subjects,(Experimental group, high fiber and sugar free biscuit group) All 30 subjects consume 3 serving of high-fiber, and sugar free biscuits(containing 16 grams of fiber) daily.
Post-period:
Blood samples of all 60 subjects will be collected to compare with period-I and period-II at the first day of 9th week.
Report of expectation:
The purpose of this study is to help the pre-diabetic subjects to reduce the risk of becoming diabetic through the consuming of high fiber and sugar free biscuits and nutrition education.
778 studies on the registry are indexed under Glucose Intolerance; 129 are open to participants now.
This study's planned enrollment of 60 is close to the median of 60 across 645 interventional studies indexed under Glucose Intolerance.
Browse Glucose Intolerance studies →China Medical University Hospital is the lead sponsor of 464 studies on the registry; 116 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
High fiber sugar free biscuit will regulate Blood sugars.
Dietary Supplement: High fiber sugar free biscuit
Dosage form:Biscuit, Dosage:1.94gram fiber/slice, Frequency:9 slices/meal;3 times/day. Duration:8 weeks
Also known as: Taiwan IMeI high fiber sugar free biscuit
HbA1c
The investigators expect the HbA1c will be greatly improved at the end of the study.
Time frame: up to 8 weeks
Insulin, Fasting Glucose,Ketone Body, Fructosamine.
The investigators expect the following data will be improved at the end of the study:Insulin, Fasting Glucose, Ketone Body, Fructosamine.
Time frame: 8 weeks
This study is status unknown, as verified in Apr 2011. You cannot join it, but the record below documents what was studied.
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China Medical University Hospital