An observational study in X-linked Hypohidrotic Ectodermal Dysplasia, sponsored by University Hospital Erlangen. Completed at 1 site in Germany. Open to male participants aged 6 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-01-08.
Sponsored by University Hospital Erlangen · Observational
X-linked hypohidrotic ectodermal dysplasia (XLHED) is a complex genetic disorder characterized by lack of sweat, sebaceous, submucous, Meibomian and mammary glands, sparse hair and eyebrows, and oligodontia. Insufficient function of the respective glands may lead to chronic inflammatory processes in airways and eyes of the affected individuals. The investigators will quantify sweat glands of XLHED patients, assess chronic conjunctivitis and blepharitis in conjunction with quantitative and/or qualitative alterations of lacrimal fluid in these subjects, evaluate lung function and assess chronic inflammatory processes in the airways by NO measurements. The data should provide a basis for genotype-phenotype correlations.
20 studies on the registry are indexed under Ectodermal Dysplasia 1, Anhidrotic; 1 is open to participants now.
This study's enrollment of 38 is above the median of 33 across 16 observational studies indexed under Ectodermal Dysplasia 1, Anhidrotic.
Browse Ectodermal Dysplasia 1, Anhidrotic studies →University Hospital Erlangen is the lead sponsor of 28 studies on the registry; 3 are open to participants now.
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subjects with X-linked hypohidrotic ectodermal dysplasia (XLHED) and healthy controls
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This study is completed, as verified in Jan 2014. You cannot join it, but the record below documents what was studied.
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Ectodermal Dysplasia 1, Anhidrotic →
University Hospital Erlangen