An observational study in Stroke, sponsored by Baltimore VA Medical Center. Status unknown at 3 sites in United States. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2024-08-06.
Sponsored by Baltimore VA Medical Center · Observational
Stroke, a leading cause of disability in the aging population, increases the risk for diabetes, subsequent stroke recurrence, and cardiovascular disease complications. The downsizing of private and federal health care resources, along with the anticipated increase in stroke rates as our population ages, mandate that alternative strategies be developed to reduce the public health burden of stroke. This pilot study may facilitate our knowledge of the timing of paretic leg muscle atrophy, fiber type shift, and the progression of worsening of glucose tolerance after stroke. Knowledge of the skeletal muscle changes occurring in the sub-acute stroke period is essential to create new guidelines incorporating exercise rehabilitation, much like cardiac rehabilitation, in order to facilitate and improve the health care of veteran stroke survivors.
The vast majority of cerebrovascular accidents are reported in persons older than 55 years of age and occur in over 780,000 persons each year in the U.S. As our adult population ages, the number of strokes in the United States is anticipated to double, reaching nearly 1.5 million annually by the year 2050. Following stroke, patients remain at continued high risk for recurrent stroke with almost a third of them suffering recurrent stroke within 5 years, even despite optimal medical management. Age and cardiac disease are among the most important longitudinal predictors of cardiovascular health outcomes and survival after stroke. Notably, 75% of chronic stroke survivors have residual disability emphasizing the need for rehabilitation strategies.
Knowledge of the skeletal muscle changes that occur in the early phases after stroke is essential to create new guidelines which incorporate exercise rehabilitation, much like cardiac rehabilitation, in order to facilitate and improve the health care of stroke survivors.
7,441 studies on the registry are indexed under Stroke; 2,012 are open to participants now.
This study's planned enrollment of 100 is below the median of 160 across 1,729 observational studies indexed under Stroke.
Browse Stroke studies →Baltimore VA Medical Center is the lead sponsor of 19 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Acute Stroke
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Muscle biopsy Exclusion Criteria:
longitudinal follow-up after stroke
Change in body composition
Muscle mass
Time frame: change in muscle mass from baseline to 3 months
Change in glucose
glucose levels
Time frame: change in glucose from baseline to 3 months
Change in physical function
walk distance
Time frame: change in walk distance from baseline to 3 months
Plan to share: No
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This study is status unknown, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.
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Baltimore VA Medical Center