An interventional study of volume control and pressure control in Herniation of Lumbar Vertebral Disc, sponsored by Yonsei University. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 65 Years. Per ClinicalTrials.gov, last updated 2012-02-03.
Sponsored by Yonsei University · Not applicable, Interventional, and Supportive care
Prone position in spinal surgery can increase airway pressure and decrease dynamic lung compliance by a frame used for postural stabilization. Also, it can increase hemodynamic instability such as reduced blood pressure by aggravating cardiac index.
Former study shows pressure controlled ventilation on the pulmonary mechanics can improve alveolar use and oxygenation than volume controlled ventilation. The latter one means controlling a patient's breathing completely through tidal volume and set breathing rate. This could be useful for the patients not possible to breath by themselves because it guarantees the perfect breathing.
The pressure controlled ventilation is used when there is a possibility to change a patient's environment. The pressure will be maintained steadily, but volume and flux will be changed. That means through the pressure already set, the whole breathing will be maintained from the beginning to end. If a patient's resistance is increased, the volume will be decreased even though the way of blood pressure control is same. However, the tidal volume per minute can be controlled somewhat and barotrauma can be decreased by controlling respiratory rate. Through this study, we are expecting the pressure controlled ventilation in prone position can improve lung mechanics and oxygenation.
1,096 studies on the registry are indexed under Hernia; 132 are open to participants now.
This study's enrollment of 40 is below the median of 80 across 739 interventional studies indexed under Hernia.
Browse Hernia studies →Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Peak airway pressure were set to deliver a tidal volume of 10 ml/kg of ideal body weight
Procedure: volume control
After anesthetic induction, anesthesia maching were set to deliver a tidal volume of 10 ml/kg of ideal body weight
Procedure: pressure control
Volume controlled ventilation of tidal volume 10 ml/kg
Pressure controlled ventilation for peak airway pressure to deliver tidal volume 10 ml/kg.
peak airway pressure
Record peak airway pressure on anesthesia mechanical ventilator after anesthesia induction and 30 minutes after prone positioning.
Time frame: 30 minutes after prone position
This study is completed, as verified in Feb 2012. You cannot join it, but the record below documents what was studied.
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Yonsei University