An interventional study of Mupirocin and Rifampin+Clindamycine or Trimehoprimsulfa in Throatcarriers of MRSA, sponsored by Region Skane. Completed at 6 sites in Sweden. Open to participants aged 5 Years and older. Per ClinicalTrials.gov, last updated 2017-08-22.
Sponsored by Region Skane · Not applicable, Interventional, and Treatment
The purpose of this study is to determine whether systemic antibiotic treatment with rifampicin and clindamycine or trimethoprim-sulfa in addition to topical treatment with mupirocin is more effective than only topical treatment to eradicate MRSA in throatcarriers
Region Skane is the lead sponsor of 372 studies on the registry; 113 are open to participants now.
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Colonized with MRSA in the throat Older than 5 years MRSA-bacteria sensitive for Rifampicin and Clindamycine or Trimethoprimsulfa -
Exclusion Criteria:
Allergy to the studymedication Healthcareworkers Pregnancy Active infection with MRSA Immunosuppression Treatment with other antibiotic during the studyperiod
Topical treatment
Drug: Mupirocin · Drug: Rifampin+Clindamycine or Trimehoprimsulfa
Rifampicin 10 mg/kgx1xVII Clindamycine 300 mgx3xVII Trimethoprimsulfa 400mg/80mg 2x2
Drug: Rifampin+Clindamycine or Trimehoprimsulfa
Topical in the nose 3 times daily for 5 days
Rifampicin 10 mg/kgx1xVII Clindamycine 300 mgx3 Trimethoprimsulfa 400mg/80mg 2x2
Culture for MRSA
Time frame: after 6 months
This study is completed, as verified in May 2015. You cannot join it, but the record below documents what was studied.
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Region Skane