An observational study in Diabetes, sponsored by University Hospital, Gentofte, Copenhagen. Completed at 1 site in Denmark. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-01-23.
Sponsored by University Hospital, Gentofte, Copenhagen · Observational
PURPOSE
The goal of the present project is to unravel the importance of bile acid-induced GLP-1 secretion (via the G protein-coupled receptor TGR5) in human physiology.
In the present study the investigators examine the GLP-1 secretion in healthy subjects and cholecystectomised patients. Thereby the investigators aim to show, that cholecystectomised patients have reduced bileflow after a meal, and as a consequence exhibit a diminished GLP-1 response as compared to healthy subjects.
University Hospital, Gentofte, Copenhagen is the lead sponsor of 154 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Healthy subjects and cholcystectomised patients (chol)
Inclusion Criteria: (Healthy)
Inclusion Criteria: (cholecystectomy group)
Exclusion Criteria: (both groups)
GLP-1 secretion
Time frame: Postprandial
This study is completed, as verified in Jan 2013. You cannot join it, but the record below documents what was studied.
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University Hospital, Gentofte, Copenhagen