An observational study in Back Pain, sponsored by Canadian Memorial Chiropractic College. Completed at 1 site in Canada. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-09-25.
Sponsored by Canadian Memorial Chiropractic College · Observational
Manual treatment offers benefit to some patients suffering from back pain but little is known about which of the many tissue layers are affected. This study will help identify which tissues may be stimulated sufficiently to be a source for the clinical effects of treatment and to prioritize future work to understand mechanisms of back pain and to improve care.
Current soft-tissue ultrasound elastography techniques, under static condition, will be extended to quantify relative displacement and strains(active and passive)across the depth of tissue strata that arise from small amplitude motions during continuous passive motion clinical procedures and in weight bearing postures. Relative movement of the stratified layers of the back, from treatment and task-generated perturbations, will enable the elastography interrogation of the tissue.
Tissue displacement and strain differs dependent on comparable tasks, in recumbent vs upright postures and muscular activation.
Relative muscle activity is significantly related to muscle strain ratio.
Displacement and strain decrease monotonically as depth of paraspinal tissue from the surface increases.
Change in tissue displacement and strains differ between healthy and unhealthy individuals when change in muscle activity and tissue layer are taken into account.
2,373 studies on the registry are indexed under Back Pain; 284 are open to participants now.
This study's enrollment of 101 is close to the median of 100 across 357 observational studies indexed under Back Pain.
Browse Back Pain studies →Canadian Memorial Chiropractic College is the lead sponsor of 17 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Group 1: Fifteen healthy volunteers from Canadian Memorial Chiropractic College (CMCC) community.
Group 2: 30 Subjects (15 healthy volunteers and 15 chronic low back pain)
Exclusion Criteria:
Volunteers taking anti-inflammatory or antihistamine medications will be asked to discontinue their use 3 days before testing.
The quantitative tissue displacement and strains.
These parameters may be considered as total cumulative displacement and strain over the recording interval or smaller epochs sequentially over time. After analysis completion, power and effect sizes will be calculated for the various parameters being studied. In cases where statistical power is found to be insufficient, calculation for appropriate sample size estimates will be compiled to guide future work. Secondary analyses will explore linear vs non-linear representations of the data. The best fit of linear/nonlinear correlations will be used to describe all muscle relationships.
Time frame: baseline and 6 weeks
Timing of change in the relative myoelectric activity.
These parameters may be considered as total cumulative displacement and strain over the recording interval or smaller epochs sequentially over time. After analysis completion, power and effect sizes will be calculated for the various parameters being studied. In cases where statistical power is found to be insufficient, calculation for appropriate sample size estimates will be compiled to guide future work. Secondary analyses will explore linear vs non-linear representations of the data. The best fit of linear/nonlinear correlations will be used to describe all muscle relationships.
Time frame: baseline and 6 weeks
Strain ratio in the context of a series of motions in upright/recumbent postures and in healthy/chronic low back pain volunteers.
These parameters may be considered as total cumulative displacement and strain over the recording interval or smaller epochs sequentially over time. After analysis completion, power and effect sizes will be calculated for the various parameters being studied. In cases where statistical power is found to be insufficient, calculation for appropriate sample size estimates will be compiled to guide future work. Secondary analyses will explore linear vs non-linear representations of the data. The best fit of linear/nonlinear correlations will be used to describe all muscle relationships.
Time frame: baseline and 6 weeks
This study is completed, as verified in Sep 2012. You cannot join it, but the record below documents what was studied.
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Canadian Memorial Chiropractic College