An observational study in Liver Diseases and Hepatectomy, sponsored by Nottingham University Hospitals NHS Trust. Status unknown at 1 site in United Kingdom. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2010-10-14.
Sponsored by Nottingham University Hospitals NHS Trust · Observational
The aim of this study is to characterize Kupffer cell activity and activation of the innate immune response in the early phase of liver regeneration after right hepatectomy. The investigators hypothesise that liver regeneration after right hepatectomy in humans is associated with Kupffer cell activation and initiation of the innate immune response and that impaired liver regeneration, liver failure and sepsis following liver resection are associated with Kupffer cell dysfunction and an impaired innate immune response. The objectives for this study are to characterise Kupffer cell activity and the innate immune response in human liver before and after right hepatectomy.
2,081 studies on the registry are indexed under Liver Diseases; 390 are open to participants now.
This study's planned enrollment of 20 is below the median of 167 across 681 observational studies indexed under Liver Diseases.
Browse Liver Diseases studies →Nottingham University Hospitals NHS Trust is the lead sponsor of 104 studies on the registry; 19 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients undergoing right hepatectomy for colorectal liver metastases.
Exclusion Criteria:
Intervals from inflow division.
Procedure: Liver biopsy
0, 30, 60, 90 min post inflow-division
This study is status unknown, as verified in Oct 2010. You cannot join it, but the record below documents what was studied.
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Nottingham University Hospitals NHS Trust