CClinicalTrials.gg
CompletedNCT01185314PIONEERUpdated Aug 8, 2011

To Study the Changes in Protein in Lung Cells of Asian Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

An interventional study of Testing for mutation status in Non Small Cell Lung Cancer, sponsored by AstraZeneca. Completed at 36 sites in 7 countries. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2011-08-08.

Sponsored by AstraZeneca · Not applicable, Interventional, and Screening

Phase
Not applicable
Study type
Interventional
Enrollment
1,270
Allocation
Not applicable
Ages
20 Years and older
Sex
All
01

Study summary

The purpose of this study is to study the changes in protein in lung cells of Asian patients with advanced non small cell lung cancer.

Read the detailed description

A molecular epidemiology study in Asian patients with advanced NSCLC of adeno histology to assess EGFR mutation status.

02

Conditions studied

  • Non Small Cell Lung Cancer

Keywords

  • NSCLC, EGFR mutation
03

In context

Lung Neoplasms

7,243 studies on the registry are indexed under Lung Neoplasms; 1,557 are open to participants now.

This study's planned enrollment of 1,270 is above the median of 60 across 5,295 interventional studies indexed under Lung Neoplasms.

Browse Lung Neoplasms studies →

Lead sponsor

AstraZeneca is the lead sponsor of 3,429 studies on the registry; 270 are open to participants now.

Of its 357 completed or terminated interventional studies of FDA-regulated products, 173 (48%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Histological or cytologically confirmed advanced Non small cell lung cancer of adeno histology NSCLC treatment naive Availability of cancer tissue or cytology sample

Exclusion criteria

Exclusion Criteria:

  • Involvement in the planning and/or conduct of the study Previous enrollment in the present study
05

Study design

Phase
Not applicable
Primary purpose
Screening
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
1,270 participants (estimated)

Study arms

  • Other
    1

    EGFR mutation testing

    Procedure: Testing for mutation status

Interventions

  • ProcedureTesting for mutation status

    EGFR mutation test

06

What researchers measure

Primary outcomes

  1. EGFR mutation status of Asian patients with advanced NSCLC

    Time frame: Samples will be tested after informed consent. Mutation results will be available within 1-3 weeks.

07

Study locations

36 sites
  • Research Site
    Beijing, Beijing, China
  • Research Site
    Guangzhou, Guangdong, China
  • Research Site
    Shijiazhuang, Hebei, China
  • Research Site
    Zhengzhou, Henan, China
  • Research Site
    Wuhan, Hubei, China
  • Research Site
    Changchun, Jilin, China
  • Research Site
    Shenyang, Liaoning, China
  • Research Site
    Jinan, Shandong, China
  • Research Site
    Shanghai, Shanghai, China
  • Research Site
    Taiyuan, Shanxi, China
  • Research Site
    Chengdu, Sichuan, China
  • Research Site
    Tianjin, Tianjin, China
  • Research Site
    Hong Kong, Hong Kong
  • Research Site
    Rohini, Delhi, India
  • Research Site
    Vadodara, Gujarat, India
  • Research Site
    Kochi, Kerala, India
  • Research Site
    Mumbai, Maharashtra, India
  • Research Site
    Pune, Maharashtra, India
  • Research Site
    Chennai, India
  • Research Site
    Kolkata, India
  • Research Site
    Cebu City, Philippines
  • Research Site
    Manila City, Philippines
  • Research Site
    Pasay City, Philippines
  • Research Site
    Quezon City, Philippines
  • Research Site
    Taguig City, Philippines
  • Research Site
    Chiayi, Taiwan
  • Research Site
    Kaohsiung, Taiwan
  • Research Site
    Taichung, Taiwan
  • Research Site
    Tainan, Taiwan
  • Research Site
    Taipei, Taiwan
  • Research Site
    Tao-Yuan, Taiwan
  • Research Site
    Bangkok, Thailand
  • Research Site
    Chiang Mai, Thailand
  • Research Site
    Songkla, Thailand
  • Research Site
    Hanoi, Vietnam
  • Research Site
    Ho Chi Minh City, Vietnam
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 8, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01185314
Lead sponsor
AstraZeneca
First posted
Aug 19, 2010
Start date
Sep 2010
Primary completion
Jul 2011
Completion
Jul 2011
Last update
Aug 8, 2011

Study contacts

Guy Yeoman, MBBS, MFPM
study director · AstraZeneca
Robin Meng, MD, PhD
study chair · AstraZeneca Taiwan
Yang Pan-Chyr, MD, PhD
principal investigator · National Taiwan University College of Medicine

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2011. You cannot join it, but the record below documents what was studied.

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