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Status unknownNCT01171235Updated Jul 28, 2010

Study of Biomarker From Blood and Tissue of Head and Neck Carcinoma

An observational study in Laryngeal Neoplasms and Pharyngeal Neoplasms, sponsored by Southern Medical University, China. Status unknown. Open to participants aged 15 Years to 75 Years. Per ClinicalTrials.gov, last updated 2010-07-28.

Sponsored by Southern Medical University, China · Observational

The sponsor has not verified this record recently (last verified Mar 2009), so the status shown — last known as Enrolling by invitation — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
200
Ages
15 Years to 75 Years
Sex
All
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Study summary

The aim of the study is to find for one or more serum or tissue markers of molecular biology in head and neck cancer patients used for early diagnosis, predicting prognosis and being sensitive to chemotherapy and radiotherapy

Read the detailed description

Head and neck malignant tumors, especially nasopharyngeal carcinoma in southern China with the high incidence, its incidence, treatment, prognosis or tumor markers in serum has been a hot research with little progress.In our study, we collect NPC-based collection including the blood samples of laryngeal, hypopharyngeal cancer, separating serum and white blood cells stored in -80 degrees,while tissues are frozen in liquid nitrogen and embedded in paraffin。 Patient treatment and prognosis are combined in order to find for markers of molecular biology used for early diagnosis, predicting prognosis and being sensitive to chemotherapy and radiotherapy.

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Conditions studied

  • Laryngeal Neoplasms
  • Pharyngeal Neoplasms

Keywords

  • Laryngeal Neoplasms
  • Pharyngeal Neoplasms
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In context

Neoplasms

9,365 studies on the registry are indexed under Neoplasms; 2,489 are open to participants now.

This study's planned enrollment of 200 is close to the median of 204 across 1,683 observational studies indexed under Neoplasms.

Browse Neoplasms studies →

Lead sponsor

Southern Medical University, China is the lead sponsor of 31 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
15 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

all of nasopharyngeal carcinoma, hypopharyngeal carcinoma or laryngeal carcinoma visited at ENT department of NanFang hospital

Inclusion criteria

  • all of nasopharyngeal carcinoma
  • hypopharyngeal carcinoma or laryngeal carcinoma visited at ENT department of NanFang hospital

Exclusion criteria

Exclusion Criteria:

  • all of above patients whose anticipated survival duration were less than 6 months
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
200 participants (estimated)
Biospecimen retention
Samples with dna
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Study locations

No study locations are listed for this record.

07

References and documents

Publications

  • Yu BL, Peng XH, Zhao FP, Liu X, Lu J, Wang L, Li G, Chen HH, Li XP. MicroRNA-378 functions as an onco-miR in nasopharyngeal carcinoma by repressing TOB2 expression. Int J Oncol. 2014 Apr;44(4):1215-22. doi: 10.3892/ijo.2014.2283. Epub 2014 Jan 28. PubMed 24481647 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 28, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01171235
Lead sponsor
Southern Medical University, China
First posted
Jul 28, 2010
Start date
Jul 2010
Primary completion
Dec 2011 (estimated)
Completion
Dec 2012 (estimated)
Last update
Jul 28, 2010

Study contacts

Ping Xiang Li, doctor
study director · E.N.T department of NanFang hospital

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2009. You cannot join it, but the record below documents what was studied.

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