An observational study in Breast Cancer and Sentinel Node, sponsored by Catharina Ziekenhuis Eindhoven. Completed at 1 site in Netherlands. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-07-19.
Sponsored by Catharina Ziekenhuis Eindhoven · Observational
Rationale: Like in primary breast cancer, prognosis in recurrent breast cancer is correlated with regional lymph node status. Therefore, axillary staging may be warranted in patients with recurrent disease and intact axillary nodes, although this has not been described in guidelines yet. The lymphatic drainage pathways in the breast and/or axilla could have been changed due to prior surgery and/or radiotherapy. These aberrant drainage pathways could be detected with lymphatic mapping and sentinel node biopsy (SNB), leading to a more accurate staging.
Objective: To assess the technical feasibility of lymphoscintigraphy after prior breast surgery. A second goal is to investigate whether or not previous breast surgery (with or without radiotherapy) significantly changes the lymphatic drainage pathways of the breast.
Catharina Ziekenhuis Eindhoven is the lead sponsor of 80 studies on the registry; 14 are open to participants now.
Counted across the registry records on this site, refreshed daily.
We included patients that received BCT with SNB and/or ALND for primary breast cancer located in the upper-outer quadrant of one breast at least 3 years before this analysis. Patients were excluded if they had breast surgery for other reasons than breast cancer, had recurrent breast cancer or had a former allergic reaction to 99mTc-colloidal-albumin.
44 patients were included and were divided into two groups according to previous surgical treatment of the axilla, being the sentinel node biopsy group and the Axillary Lymph Node Dissection group
Exclusion Criteria:
All women who has Sentinel Node Biopsy as their primary treatment of the axilla
Radiation: Lymphoscintigraphy
All women who had Axillary Lymph Node Dissection as primary axillary treatment
Radiation: Lymphoscintigraphy
in all women a lymphoscintigraphy was done to investigate drainage patterns of a previous operated breast and axilla
Also known as: 99mTc-colloidal-albumin
This study is completed, as verified in Jul 2010. You cannot join it, but the record below documents what was studied.
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Catharina Ziekenhuis Eindhoven