CompletedNCT01149226Updated Jun 10, 2011

Effects of Chloral Hydrate on Induction, Maintenance, and Recovery From Sevoflurane Anesthesia in Day-case Pediatric Surgery

An interventional study of chloral hydrate in Pediatric, sponsored by Yonsei University. Completed at 1 site in Korea, Republic of. Open to participants aged 1 Year to 5 Years. Per ClinicalTrials.gov, last updated 2011-06-10.

Sponsored by Yonsei University · Not applicable and Interventional

Phase: Not applicable
Study type: Interventional
Enrollment: 100
Allocation: Randomized
Ages: 1 Year to 5 Years
Sex: All

Study summary

Effects of Choral Hydrate on Induction, Maintenance, and Recovery from Sevoflurane Anesthesia in Day-case Pediatric Surgery

Conditions studied

Pediatric

Keywords

pediatric patients
ASA physical status I or II
aged between 1-5 yrs

In context

Lead sponsor

Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 1 Year to 5 Years
Sexes eligible: All
Accepts healthy volunteers: No

Inclusion criteria

ASA I or II
1-5 years children
elective day-case orchiopexy

Exclusion criteria

Exclusion Criteria:

congenital hear disease
renal disease
liver disease
growth retardation
coagulopathy

Study design

Phase: Not applicable
Allocation: Randomized
Intervention model: Parallel assignment
Masking: Double (Participant, Care provider)
Enrollment: 100 participants (actual)

Study arms

Placebo comparator
placebo control
Drug: chloral hydrate
Experimental
oral medication chloral hydrate
Drug: chloral hydrate

Interventions

Drugchloral hydrate
30 min before the induction of anesthesia, chloral hydrate (40 mg/kg) or placebo was administered to the children orally.

What researchers measure

Primary outcomes

Preoperative Anxiety
Preoperative Anxiety Score Modified Yale Preoperative Anxiety Scale (YPAS, 0-100) was assessed by observer Anesth Analg 1997;85:783-8
Induction Compliance
Induction Compliance Checklist Induction Compliance Checklists (ICC, 0-10) was assessed by anesthetist Anesthesiology 1998;89:1147-56
Postoperative Pain
-Postoperative Pain Score Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale (0-10) was assessed by observer Am J Crit Care. 2010 Jan;19(1):55-61
Posthospitalization Behavior
Posthospitalization Behavior Questionnaire Posthospitalization Behavioural Questionnaire (27-135)was sent to all parents of children Paediatr Anaesth. 2001 Nov;11(6):719-23.

Study locations

1 site

Severance Hospital
Seoul, 120-752, Korea, Republic of

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Jun 10, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT01149226
Lead sponsor: Yonsei University
First posted: Jun 28, 2010
Start date: May 2010
Primary completion: Dec 2010
Completion: Dec 2010
Last update: Jun 10, 2011

Oversight

Data monitoring committee: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2011. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies from this sponsor

Yonsei University

Start the discussion