An observational study in Diabetes Mellitus, sponsored by Glostrup University Hospital, Copenhagen. Completed at 1 site in Denmark. Open to participants aged 17 Years to 80 Years. Per ClinicalTrials.gov, last updated 2010-12-08.
Sponsored by Glostrup University Hospital, Copenhagen · Observational
The overall objective is to investigate, whether retinal blood vessel diameter change during the energy consuming dark adaptation process and if responses vary between low and high blood glucose.
All subjects are being studied using the same procedure. The study schedule takes place from 8 a.m. to 12 a.m. every time. Each subject shows up on one single day. Subjects are to show up fasting overnight with a break in insulin and/or oral antidiabetic treatment.
The study eye of each subject will be selected by randomisation. We seek to have an equal distribution of right and left eyes overall.
A first set of images will be taken after 5 minutes in "standardised daylight", in a room without light from outside, which eliminates any concerns about weather variations. After this the room is completely darkened. 2 set of images will be taken in the dark adapted state after 20 and 40 minutes. Subsequently the patient ingests the OGTT and will reach maximum blood glucose level after about 60-90 minutes. At this time, the subjects undergo the same "photo session" as above with high blood glucose levels.
10,925 studies on the registry are indexed under Diabetes Mellitus; 1,319 are open to participants now.
This study's enrollment of 14 is below the median of 233 across 2,220 observational studies indexed under Diabetes Mellitus.
Browse Diabetes Mellitus studies →Glostrup University Hospital, Copenhagen is the lead sponsor of 104 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Subjects with diagnosed Type 2 diabetes mellitus with none or minimal diabetic retinopathy.
Exclusion Criteria:
This group includes subjects diagnosed with type 2 diabetes mellitus with none or minimal diabetic retinopathy.
Dietary Supplement: Oral Glucose Tolerance Test (OGTT)
75 g of glucose dissolved in 250 mL water.
Also known as: OGTT
Vessel caliber
Time frame: 1 day
Blood glucose level
Capillary samples.
Time frame: 1 day
This study is completed, as verified in Dec 2010. You cannot join it, but the record below documents what was studied.
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Glostrup University Hospital, Copenhagen