An interventional study of Access to diagnostic test in Acute Respiratory Tract Infection, sponsored by Göteborg University. Completed at 1 site in Sweden. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-05-31.
Sponsored by Göteborg University · Not applicable, Interventional, and Diagnostic
Viral respiratory infections are common worldwide. It has been suggested that nucleic acid amplification tests, enabling a rapid etiologic diagnosis, may be useful in reducing antibiotic prescriptions rates. The objective of this study was to evaluate if access to a multiplex real-time PCR method would have an impact on antibiotic prescriptions for acute respiratory tract infections (ARTIs), in primary care. Adult patients with respiratory tract infections will be prospectively included. Nasopharyngeal and throat swabs will be analyzed with a multiplex real-time PCR method, targeting 13 viruses and two bacteria. Samples will be collected during the winter season (October-April). Patients will be open-label randomised to receive a rapid result (the following day) or a delayed result (after 10+/-2 days). The investigators are planning to include approximately 400 patients. Prescription of antibiotics will be measured at initial visit as well as at a follow-up visit 10+/-2 days later. Primary endpoint is antibiotic prescription in the acute phase (initial visit) and secondary endpoint antibiotic treatment (ongoing or initiated) at follow-up visit. The hypohesis is that access to a method with the ability of providing a rapid etiologic diagnosis of respiratory infections will affect the use of antibiotics in outpatient care of adult patients with ARTI.
6,687 studies on the registry are indexed under Infections; 807 are open to participants now.
This study's enrollment of 406 is above the median of 120 across 4,200 interventional studies indexed under Infections.
Browse Infections studies →Göteborg University is the lead sponsor of 265 studies on the registry; 46 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Result of diagnostic PCR panel provided the following day
Procedure: Access to diagnostic test
Result of dagnostic PCR panel provided within 10+/-2 days at follow-up visit.
Randomization to receive a result of diagostic procedure the following day.
Antibiotic treatment prescriped at initial visit
Antibiotic prescriptions are measured as an outcome of the diagnostic procedure tested.
Time frame: Within 2 days of initial visit
Antibiotic treatment prescribed or reported at follow-up visit
Antibiotic prescriptions at follow visit are measured as an outcome of the diagnostic procedure tested.
Time frame: 10+/-2 days
This study is completed, as verified in Oct 2006. You cannot join it, but the record below documents what was studied.
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Göteborg University