An interventional study of Prophylactic CPAP Administration in Transient Tachypnea, sponsored by New York Hospital Queens. Completed at 1 site in United States. Open to participants aged 2 Minutes to 30 Minutes, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-10-06.
Sponsored by New York Hospital Queens · Not applicable, Interventional, and Prevention
Transient Tachypnea of the Newborn (TTN) is a disorder of delayed clearance of lung liquid and a common cause of admission of full term infants and late pre term infants (34 to 36 weeks) to Neonatal Intensive Care Units (NICU). Both late preterm gestational age at delivery, and mode of delivery are considered risk factors for TTN. The investigators hypothesize that CPAP administered prophylactically in the Delivery Room via a T piece based infant resuscitator Neopuff, to neonates at increased risk for TTN, would decrease the incidence of TTN and thus decrease the need for hospitalization in the NICU. This is a pilot study to evaluate the prophylactic administration of CPAP in the Delivery Room towards prevention of TTN and it's effects on natriuretic peptides.The study will be conducted as a randomized control trial after obtaining informed consents from the parents of eligible infants. Infants will be randomized to receive either experimental treatment (prophylactic CPAP) or standardized care.
39 studies on the registry are indexed under Tachypnea; 4 are open to participants now.
This study's enrollment of 138 is above the median of 100 across 30 interventional studies indexed under Tachypnea.
Browse Tachypnea studies →New York Hospital Queens is the lead sponsor of 4 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Presence of any of the following
Babies will receive prophylactic administration of CPAP (5 cm of H2O) in the DR via T piece (Neopuff)
Other: Prophylactic CPAP Administration
Provision of standard care in the Delivery Room
Other: Prophylactic CPAP Administration
EXPERIMENTAL GROUP: Babies will receive prophylactic administration of CPAP (5 cm of H2O) in the Delivery Room via T piece (Neopuff) CONTROL GROUP: Provision of standard care in the Delivery Room
Measure of incidence of TTN
Time frame: 24 hours
Need for admissions to NICU secondary to TTN
Time frame: 24 hours
levels of plasma brain natriuretic peptide compared
* Duration of tachypnea * Duration of oxygen therapy * Length of hospital (NICU) stay
Time frame: 24 hours
This study is completed, as verified in Oct 2015. You cannot join it, but the record below documents what was studied.
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New York Hospital Queens