CClinicalTrials.gg
Status unknownNCT01081860STIF-CTSUpdated Apr 27, 2010

Stiffness of the Skin and Joints in Relation to Carpal Tunnel Syndrome

An observational study in Carpal Tunnel Syndrome, sponsored by St. Antonius Hospital. Status unknown at 1 site in Netherlands. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2010-04-27.

Sponsored by St. Antonius Hospital · Observational

The sponsor has not verified this record recently (last verified Apr 2010), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
40
Ages
18 Years to 60 Years
Sex
All
01

Study summary

The exact etiology of CTS remains yet unknown. A rise in carpal tunnel pressure is well documented, but why this phenomenon occurs is yet unknown in most patients. There is an absolute or relative narrowing of the carpal tunnel, which results in a compression of the median nerve.

The investigators postulate, that a stiffer flexor retinaculum (roof of carpal tunnel) will be less compliant. As a consequence of this stiffer retinaculum the pressure in the carpal tunnel will rise more quickly in stiff patients resulting in CTS-complaints.

A relation between connective tissue composition and joint stiffness is proven. This relationship possibly extends to a relation between stiffness of the skin, joint stiffness and the prevalence of CTS.

02

Conditions studied

  • Carpal Tunnel Syndrome

Keywords

  • Carpal tunnel syndrome
  • CTS
  • Skinstiffness
  • Jointstiffness
03

In context

Carpal Tunnel Syndrome

589 studies on the registry are indexed under Carpal Tunnel Syndrome; 139 are open to participants now.

This study's planned enrollment of 40 is below the median of 90 across 127 observational studies indexed under Carpal Tunnel Syndrome.

Browse Carpal Tunnel Syndrome studies →

Lead sponsor

St. Antonius Hospital is the lead sponsor of 94 studies on the registry; 28 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients presenting with complaints of:

  • Carpal tunnel syndrome
  • Trigger finger
  • Dupuytren contracture
  • an acute trauma to the hand

Inclusion criteria

  • Caucasian
  • Carpal tunnel release OR Trigger finger OR Dupuytren OR an acute trauma to the hand

Exclusion criteria

Exclusion Criteria:

  • Hypo-/hyperthyroidism
  • Diabetes
  • Arthritis
  • Pregnancy
  • Obesity (BMI >30)
  • Anatomical anomalies
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
40 participants (estimated)

Groups and cohorts

  • Carpal tunnel syndrome

    Patients with carpal tunnel syndrome

  • Trigger finger

    Patients with trigger fingers

  • Dupuytren Contracture

    Patients with Dupuytren

  • Trauma to the hand

    Patients with an acute trauma to the hand

06

What researchers measure

Primary outcomes

  1. Joint stiffness

    The active range of motion (elbow, wrist, knee and ankle) is measured with a standard goniometer.

    Time frame: In the 1st month

  2. Stiffness of the skin

    Skinstiffness is measured with a suction cup

    Time frame: in the 1st month

Secondary outcomes

  1. Physical activities

    Boston Questionairre

    Time frame: In the 1st month

07

Study locations

1 site
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 27, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01081860
Lead sponsor
St. Antonius Hospital
First posted
Mar 5, 2010
Start date
May 2010
Primary completion
Nov 2010 (estimated)
Completion
Dec 2010 (estimated)
Last update
Apr 27, 2010

Study contacts

A.B. Mink van der Molen, dr.
principal investigator · St. Antonius Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Apr 2010. You cannot join it, but the record below documents what was studied.

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