A Phase 1 interventional study of Litebook Bright Light Box and Litebook inactivated negation ion generator (the placebo) in Anxiety, Depression and Sleep, sponsored by University of South Carolina. Completed at 1 site in United States. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-04-28.
Sponsored by University of South Carolina · Phase 1, Interventional, and Treatment
The primary aim of this research was to examine the influence of bright light on anxiety in high-anxious young adults. In an acute exposure study, participants were randomly assigned to 45 min of either (1) bright light (3,000 lux) or (2) a placebo inactivated negative ion generator. Treatments were initiated ≤1 hr after awakening. At 10 min before and 30 min after the treatments, state anxiety, mood, and blood pressure were assessed.
Following the acute exposure study, participants performed a 5-week study. Following a a 1-week baseline, participants were randomly assigned to four weeks of daily exposure to either (1) bright light (45 min/day; 3,000 lux) or (2) placebo inactivated negative ion generator, which were initiated ≤1 hr after awakening. Before and after the experiment, clinical ratings were conducted with the Hamilton Anxiety Scale, the Hamilton Depression Scale, and the Clinical Global Impressions scale (CGI). Following baseline, and following each week of treatment, blood pressure, as well as questionnaires for state anxiety, depression, mood, sleep, and side effects were assessed.
4,868 studies on the registry are indexed under Anxiety Disorders; 1,390 are open to participants now.
This study's enrollment of 33 is below the median of 80 across 4,174 interventional studies indexed under Anxiety Disorders.
Browse Anxiety Disorders studies →University of South Carolina is the lead sponsor of 191 studies on the registry; 41 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
1 week period, in which subjects followed usual schedule, though they were asked to maintain a fairly stable sleep schedule. The baseline period was used for comparison with the experimental intervention.
Randomized exposure to the 4-week experimental treatments.
Device: Litebook Bright Light Box · Device: Litebook inactivated negation ion generator (the placebo)
Four weeks of daily exposure to bright light (3,000 lux) for 45 min/day, beginning within 60 min of arising.
Also known as: Phototherapy
Four weeks of daily exposure to inactivated negative ion generator for 45 min/day, beginning within 60 min of arising
Also known as: Placebo
Spielberger State Anxiety Inventory
state anxiety questionnaire
Time frame: 5 weeks
Hamilton Anxiety
Hamilton Anxiety Questionnaire
Time frame: 5 weeks
Beck Depression Inventory
self-report depression questionnaire
Time frame: 5 weeks
Pittsburgh Sleep Quality Inventory
PSQI, a common sleep quality questionnaire
Time frame: 5 weeks
This study is completed, as verified in Apr 2021. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of South Carolina