A Phase 4 interventional study of median nerve block and median nerve block after hydro-dissection in Nerve Block, sponsored by Hopital Foch. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-09-23.
Sponsored by Hopital Foch · Phase 4, Interventional, and Treatment
The real-time visualization of a needle and nerve during an ultrasound-guided nerve block can be challenging. These difficulties may partly explain the systemic complications of local anesthetics under ultrasound. Injection of small amounts of a solution around the anesthetized nerve (hydro-dissection) has been proposed to enhance contrast outlining its borders and also to improve the visualization of the needle tip. The glucose solution 5% solution is interesting because it allows, unlike saline, to maintain the motor response with neurostimulation. The hydro-dissection can be particularly useful when one suspect hypoechoic vessels near the nerve to be anesthetized. Thereby, the nerve well demarcated and separated from the vessels, injection of local anesthetic is performed in the circumferential diffusion space (like a small pocket) without redirecting needle.
The influence of this hydro-dissection on the nerve block efficiency is unknown. The nerve block quality can be improved because the entire anesthetic is injected in contact with the nerve, but it can also be reduced due to the dilution of the local anesthetic by the glucose solution.
In this randomized study, the investigators test the hypothesis that hydro-dissection does not alter the nerve block onset time.
Hopital Foch is the lead sponsor of 208 studies on the registry; 21 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
median nerve block (6 ml lidocaine 1.5 % with adrenalin 1:200000)
Procedure: median nerve block
median nerve block (6 ml lidocaine 1.5 % with adrenalin 1:200000) after hydro-dissection (glucose 5% solution)
Procedure: median nerve block after hydro-dissection
median nerve block performed using ultrasound guidance
median nerve block performed after hydro-dissection (glucose 5% solution), both using ultrasound guidance
Onset time of sensory blockade (light touch test: total loss of sensation at the two distal phalanges of index)
Time frame: 30 minutes after injection
Onset time of sensory blockade (cold test at index finger and thenar eminence)
Time frame: 30 minutes after injection
Onset time (light touch test at thenar eminence)
Time frame: 30 minutes after injection
Onset time for motor blockade
Time frame: 30 minutes after injection
Success rate (% of patients with total light touch block at index finger within 30 min evaluation period)
Time frame: 30 minutes after injection
Successful surgical anesthesia
Time frame: 30 minutes after injection
Duration of nerve blockade
Time frame: 12 hours
Nerve block complication
Time frame: one month
Duration of the puncture procedure
Time frame: 30 minutes after the beginning of the procedure
This study is completed, as verified in Sep 2016. You cannot join it, but the record below documents what was studied.
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Hopital Foch