An interventional study of Neurally adjusted ventilatory assist, i-Servo, Maquet Nordic (Solna, Sweden) and Control (PC- or PRVC- ventilation), i-Servo, Maquet Nordic (Solna, Sweden) in Ventilation, sponsored by University of Oulu. Completed at 1 site in Finland. Open to participants aged 1 Minute to 16 Years. Per ClinicalTrials.gov, last updated 2012-05-25.
Sponsored by University of Oulu · Not applicable, Interventional, and Treatment
The purpose of this study is to find out if NAVA-technology is better in detecting patients own inspiratory efforts during mechanical ventilation than currently used flow-triggering in PRVC (pressure regulated volume controlled) ventilation, and if NAVA gives real benefits for patients or not.
The investigators study hypothesis is that NAVA-technology can detect spontaneous inspiration more accurately than currently used methods, and thus will lead to more smooth adaptation to mechanical ventilation in pediatric patients. The investigators expect this to decrease the time of ventilatory support needed.
Asynchrony means that the timing of support given by ventilator is different from patients own breathing pattern. Asynchrony during ventilatory care may increase the risk for complications, make the weaning more difficult and may affect the survival rates.
In our study we randomly treat pediatric patients needing ventilatory support with neurally adjusted ventilatory assist and pressure controlled or PRVC-ventilation. We are willing to find out if there are any special benefits for patients with each treatment mode.
University of Oulu is the lead sponsor of 138 studies on the registry; 21 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Children randomised in this arm will be treated with neurally adjusted ventilatory assist
Device: Neurally adjusted ventilatory assist, i-Servo, Maquet Nordic (Solna, Sweden)
Patients randomized to control group will be treated with pressure controlled ventilation (PC) when they are newborns and older children in this group will be treated with pressure regulated volume controlled (PRVC) ventilation.
Device: Control (PC- or PRVC- ventilation), i-Servo, Maquet Nordic (Solna, Sweden)
Treatment with neurally adjusted ventilatory assist
Treatment with PC or PRVC ventilation.
Primary outcome is the duration of mechanical ventilation
Time frame: 30minutes-3weeks
Amount of sedative medication needed
Time frame: 30minutes-3weeks
This study is completed, as verified in May 2012. You cannot join it, but the record below documents what was studied.
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University of Oulu