An observational study in Polyuria and Polydipsia, sponsored by University of Wuerzburg. Completed at 1 site in Germany. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-04-25.
Sponsored by University of Wuerzburg · Observational
The differential diagnosis of patients with polyuria/ polydipsia is often complex, but important for the therapeutic strategy.
Challenging is in particular the clinical differentiation between patients with a partial Diabetes insipidus centralis and patients with primary polydipsia as underlying disease, because both groups are associated with similar urinary osmolalities.
The determination of plasma arginine vasopressin is unusual in this context, since measurement of AVP is not reliably.
C-terminal ProVasopressin (copeptin) is secreted stoichiometrically with AVP from the neurohypophysis, but has a longer half life in the circulation, and is thus easier to measure.
Therefore, the investigators will analyze in that study the diagnostic utility of plasma copeptin in the differential diagnosis of polyuria and polydipsia.
14 studies on the registry are indexed under Polyuria; 2 are open to participants now.
Browse Polyuria studies →University of Wuerzburg is the lead sponsor of 32 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Healthy probands Patients with diabetes insipdus centralis totalis/ partials Patients with diabetes insipidus renalis Patients with primary polydipsia
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This study is completed, as verified in Nov 2010. You cannot join it, but the record below documents what was studied.
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University of Wuerzburg