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CompletedNCT01030003Updated Mar 7, 2012

Snoring in Pregnancy and Adverse Maternal and Fetal Outcomes

An observational study in Sleep Apnea Syndromes, sponsored by University of Michigan. Completed at 1 site in United States. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-03-07.

Sponsored by University of Michigan · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
1,685
Ages
18 Years and older
Sex
Female
01

Study summary

The purpose of the study is to determine the prevalence of sleep-disordered breathing in pregnant women during the third trimester of pregnancy and to investigate whether this is associated with high blood pressure in the mother and/or growth retardation in the baby.

02

Conditions studied

  • Sleep Apnea Syndromes

Keywords

  • Sleep-Disordered Breathing
  • Snoring
  • Pregnancy
  • Fetal Growth Retardation
  • Pre-Eclampsia
03

In context

Sleep Apnea Syndromes

2,162 studies on the registry are indexed under Sleep Apnea Syndromes; 290 are open to participants now.

This study's enrollment of 1,685 is above the median of 109 across 654 observational studies indexed under Sleep Apnea Syndromes.

Browse Sleep Apnea Syndromes studies →

Lead sponsor

University of Michigan is the lead sponsor of 1,476 studies on the registry; 197 are open to participants now.

Of its 162 completed or terminated interventional studies of FDA-regulated products, 128 (79%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Eligible pregnant women are those receiving prenatal care and planning on delivering at the University of Michigan.

Inclusion criteria

  • Women attending obstetric clinics at University of Michigan Hospitals.
  • Willing and able to provide informed consent.
  • Aged 18 years or older

Exclusion criteria

Exclusion Criteria:

  • Aged under 18 years
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
1,685 participants (actual)
06

What researchers measure

Primary outcomes

  1. Maternal diagnosis of hypertension

    Time frame: 0-3 months after enrollment.

Secondary outcomes

  1. Infant birth centile

    Time frame: 0-3 months after enrollment.

07

Study locations

1 site
  • University of Michigan
    Ann Arbor, Michigan 48109, United States
08

References and documents

Publications

  • O'Brien LM, Bullough AS, Owusu JT, Tremblay KA, Brincat CA, Chames MC, Kalbfleisch JD, Chervin RD. Snoring during pregnancy and delivery outcomes: a cohort study. Sleep. 2013 Nov 1;36(11):1625-32. doi: 10.5665/sleep.3112. PubMed 24179294 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 7, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01030003
Lead sponsor
University of Michigan
Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
Responsible party
Louise O'Brien (Associate Professor, University of Michigan) — Principal investigator
First posted
Dec 10, 2009
Start date
Jan 2007
Primary completion
Aug 2011
Completion
Aug 2011
Last update
Mar 7, 2012

Study contacts

Louise M O'Brien, PhD
principal investigator · University of Michigan

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2012. You cannot join it, but the record below documents what was studied.

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