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CompletedNCT01026155Updated Dec 4, 2009

Respiratory Muscle Endurance Training in Obese Patients

An interventional study of Respiratory muscle training in Obesity, sponsored by Fondation Edith Seltzer. Completed at 1 site in France. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2009-12-04.

Sponsored by Fondation Edith Seltzer · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Non-randomized
Ages
18 Years to 60 Years
Sex
All
01

Study summary

Obese patients are known to have increased work of breathing inducing dyspnea, exercise intolerance and impaired quality of life. Respiratory muscle training is known to increase respiratory muscle capacity, reduce dyspnoea and improve exercise performance in healthy subjects and respiratory patients. The investigators hypothesized that Respiratory muscle training would reduce dyspnoea, increase exercise tolerance and quality of life in obese patients.

02

Conditions studied

  • Obesity

Keywords

  • Obese patients (BMI > 30 kg / m²)
03

In context

Lead sponsor

This is the only study on the registry with Fondation Edith Seltzer as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Obese patients (BMI > 30 kg/m2), without respiratory pathology (VEMS > 80% predicted, VEMS/CV > 80%)
  • men or women
  • age between 18 and 60 years old

Exclusion criteria

Exclusion Criteria:

  • Respiratory, cardiovascular, musculoskeletal diseases
  • Alcoholism
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Respiratory muscle traininig

    Low caloric diet and physical activities + Respiratory muscle endurance training by means of isocapnic voluntary hyperpnoea

    Other: Respiratory muscle training

  • Active comparator
    Control

    Low caloric diet and physical activities

    Other: Respiratory muscle training

Interventions

  • OtherRespiratory muscle training

    Respiratory muscle endurance training by means of isocapnic voluntary hyperpnoea

06

What researchers measure

Primary outcomes

  1. Dyspnea at rest and during exercise

Secondary outcomes

  1. Exercise performance (6-min walking distance) Quality of life (SF36 questionnaire)

07

Study locations

1 site
  • Centre Bois de l'Ours
    Briançon, 05107, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 4, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01026155
Lead sponsor
Fondation Edith Seltzer
First posted
Dec 4, 2009
Last update
Dec 4, 2009

Study contacts

Bernard Wuyam, MD PhD
principal investigator · University Hospital, Grenoble

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2009. You cannot join it, but the record below documents what was studied.

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