An interventional study of Olive Oil, Palm Olein Oil, Coconut Oil in Healthy, sponsored by Malaysia Palm Oil Board. Completed at 1 site in Malaysia. Open to participants aged 20 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-06-08.
Sponsored by Malaysia Palm Oil Board · Not applicable, Interventional, and Basic science
In this study, the investigators address the research question of whether palm olein will have a positive influence on plasma total homocysteine levels in human volunteers provided with high-protein diets formulated from common Malaysian foods.
Hypothesis: There is a significant difference on the effects of the three experimental oils (palm olein, olive and coconut oil) on plasma tHy levels and the other markers of coronary heart disease (CHD) risk measured.
The experimental are comprise of 30% kcal fat, 20% kcal protein and 50% kcal carbohydrate. Each of the test fat [palm olein (POo), virgin olive oil (OO) and coconut oil (CO)] contributes to two-thirds of total dietary fat will be compared.
Three meals a day providing 2000 kcal, including breakfast, lunch and dinner will be provided for the 5-weeks period of each fat rotation.
45 volunteers are fed with normal cooking oil for 3 weeks for standardisation purpose. They were then stratified into 3 groups according to gender, homocysteine and cholesterol level. The volunteers will be randomized, blinded and will undergo a 3 arms crossover intervention. Each intervention will take 5 wk with 2 wk wash out in between.
Baseline blood samples will be taken while other blood samples will be collected at week-4 and -5 of the study.
Malaysia Palm Oil Board is the lead sponsor of 24 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Dietary Supplement: Olive Oil, Palm Olein Oil, Coconut Oil
Dietary Supplement: Olive Oil, Palm Olein Oil, Coconut Oil
Dietary Supplement: Olive Oil, Palm Olein Oil, Coconut Oil
Effect of dietary fat type in combination with high protein on plasma homocysteine levels; 5 wk each with 2 wk wash out in between
Total homocysteine
Time frame: 4th and 5th week
Lipids profile and inflammatory markers
Time frame: 4th and 5th weeks
This study is completed, as verified in Jun 2011. You cannot join it, but the record below documents what was studied.
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Malaysia Palm Oil Board