A Phase 2/3 interventional study of PolyGlycopleX (PGX) and PolyGlycopleX (PGX) in Blood Glucose, Postprandial, sponsored by Glycemic Index Laboratories, Inc. Completed at 1 site in Canada. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2009-07-09.
Sponsored by Glycemic Index Laboratories, Inc · Phase 2/3, Interventional, and Treatment
Reductions of postprandial glucose levels have been demonstrated previously with the addition of a novel viscous polysaccharide (NVP) to a glucose drink and standard white bread. This study explores whether these reductions are sustained when NVP is added to a range of commonly consumed foods.
Recently, a commercial novel viscous polysaccharide (NVP)complex has been developed which is marketed in both the USA and Canada under the trade name PGX® (PolyGlycopleX) (InovoBiologic Inc, Calgary, AB, Canada). This complex consists of three viscous non starch polysaccharides which are processed using proprietary technology (EnviroSimplex®) to produce compressed granules which delays the onset of viscosity and increases palatability of the fiber when added to food. Previously, this fibre was shown to lower postprandial glucose levels in a dose responsive manner when mixed with a glucose drink and sprinkled onto a standard white bread demonstrating that the processing did not interfere with the effectiveness of the fiber. From this study the reduction in GI was calculated to be 7 units per gram of NVP when added to a solid food, however it is not known whether this relationship would be maintained when the NVP was added to a range of commonly eaten foods. This study therefore evaluates the effect of the addition or incorporation of NVP into a range of foods on postprandial glycemia and whether the reductions in glycemic index could be predicted using.
Glycemic Index Laboratories, Inc is the lead sponsor of 8 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Control White bread containing 50g available carbohydrate
Dietary Supplement: PolyGlycopleX (PGX)
White bread and milk control
Dietary Supplement: PolyGlycopleX (PGX)
Granola control
Dietary Supplement: PolyGlycopleX (PGX)
Cornflakes and milk control
Dietary Supplement: PolyGlycopleX (PGX)
White rice control
Dietary Supplement: PolyGlycopleX (PGX)
Fruit yogurt control
Dietary Supplement: PolyGlycopleX (PGX)
Turkey dinner control
Dietary Supplement: PolyGlycopleX (PGX)
Granola
Dietary Supplement: PolyGlycopleX (PGX)
Cornflakes and milk
Dietary Supplement: PolyGlycopleX (PGX)
White Rice
Dietary Supplement: PolyGlycopleX (PGX)
Fruit yogurt
Dietary Supplement: PolyGlycopleX (PGX)
Turkey dinner
Dietary Supplement: PolyGlycopleX (PGX)
White Bread
Dietary Supplement: PolyGlycopleX (PGX)
White bread
Dietary Supplement: PolyGlycopleX (PGX)
Granola
Dietary Supplement: PolyGlycopleX (PGX)
2.5 grams of PGX
5.0 grams of PGX
0 grams of PGX
Relative Blood glucose response of food with and without NVP
Time frame: Acute blood glucose response measured at 0, 15,30,45,60,90 and 120 min
This study is completed, as verified in Jul 2009. You cannot join it, but the record below documents what was studied.
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Glycemic Index Laboratories, Inc