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CompletedNCT00893672RAREUpdated May 6, 2009

Comparison of Two Chest Radiograph Prescription Strategies in Intensive Care Unit

An observational study in Patient Care, Quality of Health Care and Intensive Care Units, sponsored by Assistance Publique - Hôpitaux de Paris. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2009-05-06.

Sponsored by Assistance Publique - Hôpitaux de Paris · Observational

Study type
Observational
Model
Case-crossover
Time perspective
Prospective
Enrollment
849
Ages
18 Years and older
Sex
All
01

Study summary

Current guidelines recommend Routine daily chest radiographs (CXRs) for mechanically ventilated patients in intensive care units (ICUs). However, some ICUs have shifted to an On-demand strategy, in which this CXR is only prescribed if warranted by the patient's status at the morning physical examination. Here the investigators compared Routine and On-demand strategies in 21 French ICUs. The working hypothesis was that CXR prescriptions would fall by at least 20% with the On-demand strategy, with no reduction in quality of care.

Read the detailed description

Based on a cluster-randomized two-period two-strategies cross-over design, respectively 11 and 10 participating ICUs applied the Routine and On-demand strategies during the first period, each enrolling 20 consecutive patients requiring mechanical ventilation for at least two days. Each ICUs applied then applied the alternative strategy during the second period, again enrolling 20 consecutive patients.

02

Conditions studied

  • Patient Care
  • Quality of Health Care
  • Intensive Care Units
  • Ventilation, Mechanical

Keywords

  • Radiography, Thoracic
  • Intensive Care Units
  • Ventilation, mechanical
  • Matched-Pair Analysis
03

In context

Lead sponsor

Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,505 studies on the registry; 1,006 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

All newly admitted adult patients receiving mechanical ventilation at the time of the morning visit in ICU

Inclusion criteria

  • All newly admitted adult patients receiving mechanical ventilation at the time of the morning visit-any day during their ICU stay

Exclusion criteria

Exclusion Criteria:

  • Patients with mechanical ventilation lasting less than 2 days
05

Study design

Observational model
Case-crossover
Time perspective
Prospective
Enrollment
849 participants (actual)

Groups and cohorts

  • 1

    Routine strategy of chest radiograph prescription

  • 2

    On-demand strategy of chest radiograph prescription

06

What researchers measure

Primary outcomes

  1. Average number of chest radiographs per patient-day during mechanical ventilation

    Time frame: Every patient-day during mechanical ventilation.

Secondary outcomes

  1. Mortality rate in ICU

    Time frame: During the inpatient stay in ICU

  2. Average length of stay

    Time frame: During the inpatient stay in ICU

  3. Average duration of mechanical ventilation

    Time frame: During the inpatient stay in ICU

  4. Number of radiographs with new findings leading to therapeutic or diagnostic interventions

    Time frame: During the inpatient stay in ICU

07

Study locations

1 site
  • Hopital Saint-Antoine
    Paris, 75012, France
08

References and documents

Publications

  • Hejblum G, Chalumeau-Lemoine L, Ioos V, Boelle PY, Salomon L, Simon T, Vibert JF, Guidet B. Comparison of routine and on-demand prescription of chest radiographs in mechanically ventilated adults: a multicentre, cluster-randomised, two-period crossover study. Lancet. 2009 Nov 14;374(9702):1687-93. doi: 10.1016/S0140-6736(09)61459-8. Epub 2009 Nov 4. PubMed 19896184 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 6, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00893672
Lead sponsor
Assistance Publique - Hôpitaux de Paris
First posted
May 6, 2009
Start date
Dec 2006
Primary completion
Aug 2007
Completion
Apr 2009
Last update
May 6, 2009

Study contacts

Bertrand GUIDET, MD PhD
principal investigator · Assistance Publique - Hôpitaux de Paris

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2009. You cannot join it, but the record below documents what was studied.

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