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CompletedNCT00887094CGMSexerciseUpdated Aug 4, 2011

Aerobic Training, Aerobic-resistance Training and Glucose Profile (CGMS) in Type 2 Diabetes

An interventional study of Acute aerobic exercise and Acute aerobic-resistance exercise in Diabetes Mellitus, Type 2, Treatment and Exercise, sponsored by Hospital de Clinicas de Porto Alegre. Completed at 1 site in Brazil. Open to participants aged 35 Years to 65 Years. Per ClinicalTrials.gov, last updated 2011-08-04.

Sponsored by Hospital de Clinicas de Porto Alegre · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
14
Allocation
Randomized
Ages
35 Years to 65 Years
Sex
All
01

Study summary

Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.

Read the detailed description

Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.

02

Conditions studied

  • Diabetes Mellitus, Type 2
  • Treatment
  • Exercise

Keywords

  • Diabetes mellitus
  • Exercise
  • Endurance
  • Resistance
  • Continuous glucose monitoring system
03

In context

Diabetes Mellitus

10,925 studies on the registry are indexed under Diabetes Mellitus; 1,319 are open to participants now.

This study's enrollment of 14 is below the median of 80 across 8,367 interventional studies indexed under Diabetes Mellitus.

Browse Diabetes Mellitus studies →

Lead sponsor

Hospital de Clinicas de Porto Alegre is the lead sponsor of 450 studies on the registry; 61 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
35 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Type 2 diabetic patients treated with diet and metformin, 35-65 years old

Exclusion criteria

Exclusion Criteria:

  • Type 1 diabetic patients
  • Treatment with insulin or sulphonylureas or glitazones
  • Proliferative retinopathy
  • Severe autonomic neuropathy
  • Coronary artery disease
  • Baseline fasting plasma glucose>200 mg/dl
  • Peripheral artery disease
  • Amputation
  • Heart failure
  • Diabetic nephropathy
  • Renal failure
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
14 participants (actual)

Study arms

  • Experimental
    Aerobic exercise

    One bout of aerobic physical training will be performed on a cycle ergometer for 50 min

    Behavioral: Acute aerobic exercise

  • Experimental
    Aerobic-resistance exercise

    One bout of aerobic-resistance physical training will be performed on a cycle ergometer added by a strenght training for 50 min (total)

    Behavioral: Acute aerobic-resistance exercise

Interventions

  • BehavioralAcute aerobic exercise

    Aerobic exercise (on a cycle ergometer, for 50 min)

    Also known as: There are no other names

  • BehavioralAcute aerobic-resistance exercise

    Aerobic-resistance exercise (on a cycle ergometer plus strength training, for 50 min in total)

    Also known as: There are no other names

06

What researchers measure

Primary outcomes

  1. Reduction of the prevalence of hyperglycemic peaks during a 24-h period after a bout of aerobic or aerobic/resistance exercise in type 2 diabetes patients on metformin/diet therapy.

    Time frame: 24h

07

Study locations

1 site
  • Hospital de Clinicas de Porto Alegre
    Porto Alegre, RS 90035-003, Brazil
08

References and documents

Publications

  • Figueira FR, Umpierre D, Casali KR, Tetelbom PS, Henn NT, Ribeiro JP, Schaan BD. Aerobic and combined exercise sessions reduce glucose variability in type 2 diabetes: crossover randomized trial. PLoS One. 2013;8(3):e57733. doi: 10.1371/journal.pone.0057733. Epub 2013 Mar 11. PubMed 23536769 ↗
  • Figueira FR, Umpierre D, Ribeiro JP, Tetelbom PS, Henn NT, Esteves JF, Schaan BD. Accuracy of continuous glucose monitoring system during exercise in type 2 diabetes. Diabetes Res Clin Pract. 2012 Dec;98(3):e36-9. doi: 10.1016/j.diabres.2012.09.033. Epub 2012 Oct 4. PubMed 23041227 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 4, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00887094
Lead sponsor
Hospital de Clinicas de Porto Alegre
First posted
Apr 23, 2009
Start date
Jun 2009
Primary completion
Mar 2011
Completion
Apr 2011
Last update
Aug 4, 2011

Study contacts

Beatriz Schaan, PhD
principal investigator · Hospital de Clinicas de Porto Alegre

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2011. You cannot join it, but the record below documents what was studied.

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