Status unknownNCT00871091Updated Mar 30, 2009

Study Investigating Tooth Movements With Conventional and Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Supported Fixed Appliances

An interventional study of orthodontic treatment with customized archwires and orthodontic treatment with prefabricated archwires in Tooth Movement and Orthodontics, sponsored by Charite University, Berlin, Germany. Status unknown at 1 site in Germany. Open to participants aged 18 Years to 35 Years. Per ClinicalTrials.gov, last updated 2009-03-30.

Sponsored by Charite University, Berlin, Germany · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Mar 2009), so the status shown — last known as Active, not recruiting — may be out of date.

Phase: Not applicable
Study type: Interventional
Enrollment: 32
Allocation: Randomized
Ages: 18 Years to 35 Years
Sex: All

Study summary

In orthodontics, conventional fixed appliances, usually consisting of prefabricated components, require step-by-step adjustment in order to move teeth in the planned direction.

May treatment be improved with customized archwires?

Study hypotheses:

By using CAD/CAM in planning and fabrication of customized archwires, unnecessary tooth movements can be avoided and teeth can be moved on their direct path to the intended position.
The application of CAD/CAM improves reproducibility, efficiency, and quality of orthodontic treatment.

Conditions studied

Tooth Movement
Orthodontics

Keywords

CAD/CAM
orthodontics
fixed appliance
tooth movement

In context

Lead sponsor

Charite University, Berlin, Germany is the lead sponsor of 836 studies on the registry; 129 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 18 Years to 35 Years
Sexes eligible: All
Accepts healthy volunteers: No

Inclusion criteria

treatment of front teeth with fixed orthodontic appliances is indicated
complete secondary dentition
age: 18-35
in healthy general condition
patient is informed about study and agrees to participate

Exclusion criteria

Exclusion Criteria:

treatment of premolars and molars is necessary
syndromes affecting bones and teeth
cleft lip and palate
inflammation or reduction (more than 50%) of periodontium
intake of drugs affecting tooth movement and bone formation
disturbance of bone formation
disturbance of thyroidal function
pregnancy
participation in additional study affecting oral hygiene
former therapy with ionized radiation or cytostatic drugs
caries (active phase)
alcohol dependency

Study design

Phase: Not applicable
Primary purpose: Treatment
Allocation: Randomized
Intervention model: Parallel assignment
Masking: None (open label)
Enrollment: 32 participants (estimated)

Study arms

Experimental
1
CAD/CAM group, customized archwires
Procedure: orthodontic treatment with customized archwires
Active comparator
2
prefabricated archwires (superelastic)
Procedure: orthodontic treatment with prefabricated archwires
Active comparator
3
prefabricated archwires with manual adjustments
Procedure: orthodontic tx w/ conventional archwires+manual adjustments

Interventions

Procedureorthodontic treatment with customized archwires
customized arch wires depending on the amount of needed tooth movement
Also known as: SureSmile, CAD/CAM
Procedureorthodontic treatment with prefabricated archwires
prefabricated archwires depending of the needed movement of the teeth
Also known as: archwires, prefabricated, conventional orthodontic treatment
Procedureorthodontic tx w/ conventional archwires+manual adjustments
conventional archwires modified by manual adjustment, depending of needed correction
Also known as: manual adjustment, conventionel archwires

What researchers measure

Primary outcomes

Sum of differences between resulted and shortest path of tooth movements in each patient
Time frame: measurements every 14 days until end of treatment

Secondary outcomes

Difference between resulted and shortest path of movements for each tooth
Time frame: measurements every 14 days until end of treatment

Study locations

1 site

Department of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charité - Universitätsmedizin Berlin
Berlin, 14197, Germany

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Mar 30, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT00871091
Lead sponsor: Charite University, Berlin, Germany
Collaborators: German Research Foundation
First posted: Mar 30, 2009
Start date: Jan 2007
Primary completion: May 2009 (estimated)
Completion: Jun 2009 (estimated)
Last update: Mar 30, 2009

Study contacts

Paul-Georg Jost-Brinkmann, Prof

study chair · Charite - Universitätsmedizin

Oversight

Data monitoring committee: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2009. You cannot join it, but the record below documents what was studied.

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