An interventional study of Exercise in Type 2 Diabetes and Impaired Glucose Tolerance, sponsored by Karolinska Institutet. Status unknown at 1 site in Sweden. Open to participants aged 45 Years to 69 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2009-03-02.
Sponsored by Karolinska Institutet · Not applicable, Interventional, and Prevention
A sedentary lifestyle is known to be a risk factor to developing type 2 diabetes. The aim of this study was to determine the effects of adding regular Nordic walking to daily physical activity. Effects on quality of life, cardiovascular risk factors and functions in muscle cells will be determined.
Regular physical activity is known to have a beneficial effect on several factors affecting the risk of developing cardiovascular disease and type 2 diabetes. Implementing and maintaining changes of lifestyle is, however, known to be difficult. In this study we wished to investigate the effects of an exercise intervention that is feasible to most people with type 2 diabetes or at risk of developing that disease. The intervention was Nordic walking (with walking poles) for five hour per week, during four months. We chose to determine effects on health related quality of life, clinical parameters related to body weight/body composition, blood pressure, glucose metabolism, insulin resistance, blood lipids, oxygen uptake and physiological effects in skeletal muscle cells related to glucose metabolism.
On inclusion and after four months the participants were therefore subject to clinical measurements, blood samples, maximal oxygen uptake tests on an ergometer cycle and muscle biopsies at inclusion and after four months of participation. They also answered an extensive questionnaire focusing on health related quality of life.
10,925 studies on the registry are indexed under Diabetes Mellitus; 1,319 are open to participants now.
This study's planned enrollment of 213 is above the median of 80 across 8,367 interventional studies indexed under Diabetes Mellitus.
Browse Diabetes Mellitus studies →Karolinska Institutet is the lead sponsor of 1,113 studies on the registry; 267 are open to participants now.
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Exclusion Criteria:
Five hours of Nordic walking per week, during four months
Behavioral: Exercise
Control group asked not to alter lifestyle during study
Behavioral: Exercise
Nordic walking, with walking poles, five hours per week during four months
HbA1c
Time frame: at inclusion and after four months
waist circumference
Time frame: at inclusion and after four months
This study is status unknown, as verified in Feb 2009. You cannot join it, but the record below documents what was studied.
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Karolinska Institutet