An observational study in Obesity, sponsored by Washington University School of Medicine. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-09-09.
Sponsored by Washington University School of Medicine · Observational
The purpose of this study is to evaluate cefoxitin pharmacokinetics in obese surgical patients.
6,296 studies on the registry are indexed under Obesity; 1,692 are open to participants now.
This study's enrollment of 27 is below the median of 135 across 1,283 observational studies indexed under Obesity.
Browse Obesity studies →Washington University School of Medicine is the lead sponsor of 1,765 studies on the registry; 271 are open to participants now.
Of its 324 completed or terminated interventional studies of FDA-regulated products, 212 (65%) have results posted.
Counted across the registry records on this site, refreshed daily.
Surgical Patients at BJH
Exclusion Criteria:
Obese patients
Normal weight patients and volunteers
Cefoxitin Plasma Concentrations
Cefoxitin plasma concentrations
Time frame: 8 hours
Cefoxitin Tissue Concentrations
Cefoxitin tissue concentrations
Time frame: 8 hours
| Milestone | Obese Patients | Normal Weight Patients and Volunteers |
|---|---|---|
| Started | 14 | 13 |
| Completed | 14 | 13 |
| Not completed | 0 | 0 |
Cefoxitin plasma concentrations
| (µg/mL) | Obese Patients | Normal Weight Patients and Volunteers |
|---|---|---|
| Cefoxitin Plasma Concentrations | 89 ± 20 | 81 ± 33 |
Cefoxitin tissue concentrations
| (µg/mL) | Obese Patients | Normal Weight Patients and Volunteers |
|---|---|---|
| Cefoxitin Tissue Concentrations | 8.8 ± 6.6 | 26 ± 20 |
Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Obese Patients | 0/14 (0%) | 0/14 (0%) | 0/14 (0%) |
| Normal Weight Patients and Volunteers | 0/13 (0%) | 0/13 (0%) | 0/13 (0%) |
| Age, Continuous(years) | Obese Patients | Normal Weight Patients and Volunteers | Total |
|---|---|---|---|
| Mean | 52 ± 8 | 28 ± 12 | 40 ± 10 |
| Sex: Female, Male(Participants) | Obese Patients | Normal Weight Patients and Volunteers | Total |
|---|---|---|---|
| Female | 12 | 7 | 19 |
| Male | 2 | 6 | 8 |
| Race and Ethnicity Not Collected(Participants) | Obese Patients | Normal Weight Patients and Volunteers | Total |
|---|---|---|---|
| Count of participants | — | — | 0 |
| Region of Enrollment(Participants) | Obese Patients | Normal Weight Patients and Volunteers | Total |
|---|---|---|---|
| United States | 14 | 13 | 27 |
This study is completed, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Washington University School of Medicine