A Phase 1/2 interventional study of Cognitive Behavioral Therapy in Trichotillomania, sponsored by Massachusetts General Hospital. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2012-06-20.
Sponsored by Massachusetts General Hospital · Phase 1/2, Interventional, and Treatment
This study aims to develop a comprehensive Cognitive Behavioral Therapy protocol for adult patients with Trichotillomania that emphasizes relapse prevention and that addresses comorbid affective symptoms, as well. The study will compare the efficacy of CBT with a minimal attention control (MAC)condition. We hypothesize that outcome at post-treatment, 3-month, and 6-month follow-up will be better for the CBT vs. MAC condition including higher responder rates and greater reduction in hair pulling severity.
The purpose of this study is to assess the efficacy of cognitive behavioral therapy for patients with trichotillomania.
Following entry into the study, subjects will be randomized into a cognitive behavioral therapy (CBT) or a minimized attention control (MAC) condition. Subjects will be assessed with the Acceptance and Action Questionnaire (AAQ), the Affective Regulation Rating (ARR), the Barratt Impulsivity Scale (BIS-11), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Clinical Global Impressions Scale (CGI), the Difficulties in Emotion Regulation Scale (DERS), Hair Pulling Scale (HPS), Trichotillomania (TTM) Impact Scale, Psychiatric Institute Trichotillomania Scale (PITS), National Institute of Mental Health Trichotillomania Severity Scale(NIMH-TSS), the Generalized Expectancy for Negative Mood Regulation Scale (NMR), The Milwaukee Inventory for Subtypes of Trichotillomania- Adult Version (MIST-A), the Positive and Negative Affect Scale (PANAS), the Quality of Life Inventory (QOLI), the Readiness to Change Hairpulling Behavior (RCHPB), the Self-Esteem Scale (SES), the Skin Picking Scale (SPS) and the Scales of Psychological Well-Being (SPWB). Subject randomization to a treatment arm will be determined by a random number generator.
Subject change scores will be assessed for the above scales.
44 studies on the registry are indexed under Trichotillomania; 7 are open to participants now.
This study's enrollment of 38 is close to the median of 38 across 42 interventional studies indexed under Trichotillomania.
Browse Trichotillomania studies →Massachusetts General Hospital is the lead sponsor of 2,536 studies on the registry; 446 are open to participants now.
Of its 214 completed or terminated interventional studies of FDA-regulated products, 161 (75%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Minimal Attention Control
Cognitive Behavioral Therapy
Behavioral: Cognitive Behavioral Therapy
A therapy designed to help patients with response prevention skills.
Massachusetts General Hospital Hair Pulling Scale (MGHHPS)
Time frame: Baseline, weekly visits, follow-up
NIMH Trichotillomania Severity Scale (NIMH-TSS)
Time frame: Baseline, weekly visits, follow-up
NIMH Trichotillomania Impairment Scale (NIMH-TIS)
Time frame: Baseline, weekly visits, follow-up
This study is completed, as verified in Jun 2012. You cannot join it, but the record below documents what was studied.
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Massachusetts General Hospital