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CompletedNCT00721851Updated Jun 23, 2011

320-slice Coronary Computed Tomography (CT) Angiography

An observational study in Coronary Artery Stenosis, sponsored by Charite University, Berlin, Germany. Completed at 1 site in Germany. Open to participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2011-06-23.

Sponsored by Charite University, Berlin, Germany · Observational

Study type
Observational
Time perspective
Prospective
Enrollment
30
Ages
40 Years and older
Sex
All
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Study summary

The primary aim of this study is to determine the potential utility of 320-slice volume-CT for obtaining adequate diagnostic accuracy while at the same time improving image quality compared with previous generations of CT scanners and simultaneously enabling a reduction in both radiation exposure and contrast agent amount required.

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Conditions studied

  • Coronary Artery Stenosis

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In context

Coronary Stenosis

302 studies on the registry are indexed under Coronary Stenosis; 63 are open to participants now.

This study's enrollment of 30 is below the median of 200 across 132 observational studies indexed under Coronary Stenosis.

Browse Coronary Stenosis studies →

Lead sponsor

Charite University, Berlin, Germany is the lead sponsor of 836 studies on the registry; 129 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
40 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Consecutive eligible patients referred to the Charité and scheduled to undergo conventional coronary angiography.

Inclusion criteria

  • 40 years of age
  • sinus rhythm

Exclusion criteria

Exclusion Criteria:

  • prior conventional coronary angiography
  • unstable presentation
  • coronary artery bypass graft or stent
  • pregnancy or breast-feeding
  • creatinine > 2.0 mg per deciliter
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Study design

Time perspective
Prospective
Enrollment
30 participants (actual)
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Study locations

1 site
  • Charité
    Berlin, 10117, Germany
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References and documents

Publications

  • Dewey M, Zimmermann E, Laule M, Rutsch W, Hamm B. Three-vessel coronary artery disease examined with 320-slice computed tomography coronary angiography. Eur Heart J. 2008 Jul;29(13):1669. doi: 10.1093/eurheartj/ehm626. Epub 2008 Feb 7. No abstract available. PubMed 18263576 ↗
  • Zimmermann E, Dewey M. Whole-heart 320-row computed tomography: reduction of radiation dose via prior coronary calcium scanning. Rofo. 2011 Jan;183(1):54-9. doi: 10.1055/s-0029-1245629. Epub 2010 Aug 19. PubMed 20725881 ↗
  • Dewey M, de Vries H, de Vries L, Haas D, Leidecker C. The present and future of cardiac CT in research and clinical practice: moderated discussion and scientific debate with representatives from the four main vendors. Rofo. 2010 Apr;182(4):313-21. doi: 10.1055/s-0029-1245195. Epub 2010 Mar 16. PubMed 20234975 ↗
  • Dewey M, Zimmermann E, Deissenrieder F, Laule M, Dubel HP, Schlattmann P, Knebel F, Rutsch W, Hamm B. Noninvasive coronary angiography by 320-row computed tomography with lower radiation exposure and maintained diagnostic accuracy: comparison of results with cardiac catheterization in a head-to-head pilot investigation. Circulation. 2009 Sep 8;120(10):867-75. doi: 10.1161/CIRCULATIONAHA.109.859280. Epub 2009 Aug 24. PubMed 19704093 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 23, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00721851
Lead sponsor
Charite University, Berlin, Germany
First posted
Jul 25, 2008
Start date
Apr 2008
Primary completion
Dec 2008
Completion
Dec 2008
Last update
Jun 23, 2011

Study contacts

Marc Dewey, MD
principal investigator · Charité

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2009. You cannot join it, but the record below documents what was studied.

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