CompletedNCT00663533VAS-2Updated Dec 3, 2014

VAS-2 Vasectomy With the Vax-X

A Phase 1 interventional study of Vas-X in Healthy, sponsored by University of Washington. Completed at 1 site in United States. Open to male participants aged 30 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-12-03.

Sponsored by University of Washington · Phase 1, Interventional, and Prevention

Phase: Phase 1
Study type: Interventional
Enrollment: 10
Allocation: Not applicable
Ages: 30 Years to 55 Years
Sex: Male

Study summary

The purpose of this research study is to study an experimental vasectomy device called the Vas-X. This is an experimental study of this new approach to vasectomy.

Read the detailed description

The Vas-X works by stripping the lining of the vas deferens, the tube that sperm pass through during ejaculation. It is used in a way very similar to routine vasectomy, however, in a routine vasectomy, the vas is burned with an electrical device. With the Vas-X, there is no burning. The investigators are testing the Vas-X to determine whether it will offer a better way of performing a vasectomy.

The investigators will conduct this study at the University of Washington Medical Center, Seattle.

Conditions studied

Healthy

Keywords

Vasectomy
Contraception

In context

Lead sponsor

University of Washington is the lead sponsor of 1,431 studies on the registry; 226 are open to participants now.

Of its 158 completed or terminated interventional studies of FDA-regulated products, 136 (86%) have results posted.

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Who can participate

Ages eligible: 30 Years to 55 Years
Sexes eligible: Male
Accepts healthy volunteers: Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

healthy male with normal physical findings
normal testicular volume (15-30mL)
detectable sperm in ejaculates

Exclusion criteria

Exclusion Criteria:

Men with past history of
- hypertension
- significant cardiovascular
- thromboembolic disorders
- renal (including undiagnosed urinary tract bleeding)
- hepatic, prostatic and testicular disease
- prior vasectomy or scrotal surgery
- infertility
Men with a past history of drug abuse will also be excluded.

Study design

Phase: Phase 1
Primary purpose: Prevention
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Enrollment: 10 participants (actual)

Study arms

No intervention
Device study only.
Device: Vas-X

Interventions

DeviceVas-X
mechanical vasectomy device

What researchers measure

Primary outcomes

absence of sperm in ejaculated semen 6 months after vasectomy
Time frame: 6-months

Secondary outcomes

any side effects as well as degree of occlusion of the resected segment of vas deferens
Time frame: 6-months

Study locations

1 site

University of Washington
Seattle, Washington 98195, United States

References and documents

Publications

Amory JK, Jessen JW, Muller C, Berger RE. Vasectomy by epithelial curettage without suture or cautery: a pilot study in humans. Asian J Androl. 2010 May;12(3):315-21. doi: 10.1038/aja.2009.94. Epub 2010 Feb 15. PubMed 20154700 ↗

Timeline

Tracking since Sep 25, 2026

Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Apr 2008, a primary completion of Jul 2008 and a completion of Jul 2013. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered: Apr 18, 2008
First posted: Apr 22, 2008
Start: Apr 2008
Primary completionActual: Jul 2008
CompletionActual: Jul 2013
Last update: Dec 3, 2014

What these dates mean

Start.: When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.: When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.: When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.: Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.

No changes since tracking began. The registry record was last updated on Dec 3, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT00663533
Lead sponsor: University of Washington
Responsible party: John Amory (Professor, University of Washington) — Principal investigator
First posted: Apr 22, 2008
Start date: Apr 2008
Primary completion: Jul 2008
Completion: Jul 2013
Last update: Dec 3, 2014

Study contacts

John Amory

principal investigator · University of Washington

Oversight

Data monitoring committee: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2014. You cannot join it, but the record below documents what was studied.

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