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CompletedNCT00636974Updated Oct 23, 2013

A Randomised Comparison on the Dose Requirement Between, Levobupivacaine, Ropivacaine and Bupivacaine in Intrathecal Anaesthesia

An interventional study of Combined spinal epidural anaesthesia in Anesthesia, Conduction and Surgery, sponsored by Hospital Authority, Hong Kong. Completed at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-10-23.

Sponsored by Hospital Authority, Hong Kong · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
75
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

To determine and compare the effective intrathecal dose of levobupivacaine, ropivacaine and bupivacaine for 50% of patients in lower limb surgery

02

Conditions studied

  • Anesthesia, Conduction
  • Surgery

Keywords

  • Patients who are going to have regional anaesthesia for lower limbs surgery.
  • Leg Surgery.
03

In context

Lead sponsor

Hospital Authority, Hong Kong is the lead sponsor of 73 studies on the registry; 5 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All

Inclusion criteria

  • body weight=40-90kg,
  • height higher than 145cm

Exclusion criteria

Exclusion Criteria:

  • Known hypersensitivity to amide local anaesthetics,
  • patients who do not understand English and Chinese,
  • Body mass index higher than 35 kg per sq metre
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
75 participants (estimated)

Interventions

  • ProcedureCombined spinal epidural anaesthesia
06

What researchers measure

Primary outcomes

  1. Sensory block at 12th thoracic dermatome or above and successful conduct of the lower limb surgery up to 50 minutes after the intrathecal injection of the study drug

    Time frame: 50 minutes after the intrathecal injection of the study drug

07

Study locations

1 site
  • Kwong Wah Hospital
    Hong Kong, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 23, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00636974
Lead sponsor
Hospital Authority, Hong Kong
First posted
Mar 17, 2008
Start date
Jan 2006
Completion
Jul 2008
Last update
Oct 23, 2013

Study contacts

Ying Yin Lee, Dr
principal investigator · Department of Anaesthesiology, Kwong Wah Hospital
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2013. You cannot join it, but the record below documents what was studied.

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