An interventional study of Standard Behavioral Therapy and Mindfulness Based Addiction Therapy in Smoking, sponsored by University of Pittsburgh. Completed at 1 site in United States. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-04-27.
Sponsored by University of Pittsburgh · Not applicable, Interventional, and Treatment
80 nicotine dependent adults ages 18-65 who desire to quit smoking will be screened and, if eligible, enrolled and randomized to one of two four-week treatments for smoking cessation. The treatments are standard behavioral therapy and Mindfulness Based Addiction Therapy (MBAT), which is standard therapy plus mindfulness. Standard therapy and MBAT incorporate elements of widely-used tools for smoking cessation including managing craving and strong emotions, problem solving, tips on healthy eating and keeping active, and exercises based on cognitive and behavioral therapy. MBAT uniquely incorporates mindfulness practice (a relaxation therapy) into standard therapy. Participants complete questionnaires and undergo an fMRI scan at baseline and at the end of therapy (after they complete the 4 weeks of standard therapy or MBAT). During each scan, participants will complete a validated smoking-related cue paradigm and a validated affect labeling paradigm.
University of Pittsburgh is the lead sponsor of 1,385 studies on the registry; 167 are open to participants now.
Of its 8 completed or terminated interventional studies of FDA-regulated products, 4 (50%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Behavioral: Standard Behavioral Therapy
Behavioral: Mindfulness Based Addiction Therapy
Standard therapy to help participants with smoking cessation.
A novel mind body therapy that extends basic behavioral therapy principles to include the practice of mindfulness, which fosters a dispassionate approach to the experience of craving.
Smoking Cessation
Time frame: week 2 and 6 month follow-up
Exhaled CO readings
Time frame: baseline, weeks 2-4, post class follow-up, long term follow-up
Saliva Test
Time frame: baseline
Functional Magnetic Resonance Imaging
Time frame: baseline & follow-up
Urine Pregnancy Test
Time frame: baseline & follow-up
Nicotine Replacement Therapy
Time frame: Week 1
Self Reported Measures
Time frame: baseline, post class follow-up & long term follow-up
Standard Cognitive Therapy
Time frame: weeks 1-4
Mindfulness Based Cognitive Therapy
Time frame: weeks 1-4
This study is completed, as verified in Apr 2017. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of Pittsburgh