An interventional study of diazemuls, pethidine and Propofol and Alfentanil in Colonoscopy, sponsored by North District Hospital. Completed. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2007-12-03.
Sponsored by North District Hospital · Not applicable, Interventional, and Treatment
Colonoscopy is a common endoscopic procedure as an investigation of colorectal pathology. Different modalities of pain control have been described in the past. Propofol is a perfect drug for endoscopic procedure since it has the characteristic of fast onset, short half-life and early recovery. Its unfamiliarity and its potential cardiovascular and respiratory side effect make it unpopular to endoscopists. Recent reports showed propofol is safe in bolus titration by nurse in Caucasian in all endoscopic procedures. Our previous pilot study showed nurse administered propofol sedation (NAPS) is effective and safe and highly acceptable by Chinese patients. Here we conduct a randomized controlled study to compare the effectiveness of NAPS versus traditional sedation.
10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.
This study's enrollment of 194 is above the median of 66 across 8,493 interventional studies indexed under Pain.
Browse Pain studies →North District Hospital is the lead sponsor of 6 studies on the registry; 1 is open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Diazemuls-Pethidine
Drug: diazemuls, pethidine
Propofol- Alfentanil
Drug: Propofol and Alfentanil
Drug pages: Diazepam · Meperidine
5mg Diazemuls and 25mg Pethidine one min. before procedure followed by bolus doses of 2.5mg Diazemuls / 12.5mg Pethidine at the discretion of endoscopists Maximal dose of 0.2mg/kg Diazemuls and 1mg/kg Pethidine
Drug pages: Propofol · Alfentanil
Loading dose of 40-60mg or 0.8mg/kg Propofol one min. before procedure Propofol 200mg + Alfentanil 0.5mg, 1.5ml per bolus (bolus dose of 14.3mg Propofol + 35ug Alfentanil) via PCA pump No maximal dose Zero lockout time
Pain
Time frame: after recovery
sedation
Time frame: thorughout the procedure
No study locations are listed for this record.
The record gives a start of Jul 2005 and a completion of Jun 2006. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Nov 2007. You cannot join it, but the record below documents what was studied.
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Studies of the drugs tested here: Diazepam · Meperidine · Propofol · Alfentanil
North District Hospital