CClinicalTrials.gg
WithdrawnNCT00562055Updated Apr 16, 2019

Double-Blind, Four Week Trial Of [S,S]-Reboxetine And Atomoxetine In Adults With Attention Deficit Hyperactivity Disorder.

A Phase 2 interventional study of Atomoxetine and PNU-165442G; [S,S]-reboxetine in Attention Deficit Hyperactivity Disorder, sponsored by Pfizer. Withdrawn. Open to participants aged 18 Years to 55 Years. Per ClinicalTrials.gov, last updated 2019-04-16.

Sponsored by Pfizer · Phase 2, Interventional, and Treatment

Why this study was withdrawn
This study was withdrawn due to business reasons.
Phase
Phase 2
Study type
Interventional
Enrollment
0
Allocation
Randomized
Ages
18 Years to 55 Years
Sex
All
01

Study summary

This study will compare the safety and efficacy of [S,S]-reboxetine to atomoxetine in the treatment of adult patients with attention deficity-hyperactivity disorder.

02

Conditions studied

  • Attention Deficit Hyperactivity Disorder
03

In context

Hyperkinesis

729 studies on the registry are indexed under Hyperkinesis; 25 are open to participants now.

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Lead sponsor

Pfizer is the lead sponsor of 3,244 studies on the registry; 139 are open to participants now.

Of its 582 completed or terminated interventional studies of FDA-regulated products, 381 (65%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Diagnosis of Attention Deficit Hyperactivity Disorder according to DSM-IV criteria.
  2. Score of 24 or higher on the Adult ADHD Investigator Symptom Rating Scale
  3. Score of 4 or higher on the Clinician Global Impression - Severity scale

Exclusion criteria

Exclusion Criteria:

  1. Significant comorbid psychiatric diagnoses
  2. Significant risk of suicidal or violent behavior
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
0 participants (actual)

Study arms

  • Experimental
    Arm A

    Drug: PNU-165442G; [S,S]-reboxetine

  • Active comparator
    Arm B

    Drug: Atomoxetine

Interventions

  • DrugAtomoxetine
  • DrugPNU-165442G; [S,S]-reboxetine
06

What researchers measure

Primary outcomes

  1. Adult ADHD Investigator Symptom Rating Scale - Total Score

    Time frame: 4 weeks

Secondary outcomes

  1. Adult ADHD Investigator Symptom Rating Scale - Inattention Subscale Score

    Time frame: 4 weeks

  2. Adult ADHD Investigator Symptom Rating Scale - Hyperactivity/Impulsivity Subscale Score

    Time frame: 4 weeks

07

Study locations

No study locations are listed for this record.

08

References and documents

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 16, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00562055
Lead sponsor
Pfizer
First posted
Nov 21, 2007
Start date
Nov 2007
Last update
Apr 16, 2019

Study contacts

Pfizer CT.gov Call Center
study director · Pfizer
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Apr 2019. You cannot join it, but the record below documents what was studied.

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