An interventional study of atorvastatin in Heterogeneity of Cardiomyocytes Repolarisation and Autonomic Changes of Cardiomyocytes Repolarisation, sponsored by Masaryk University. Status unknown. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2007-08-24.
Sponsored by Masaryk University · Not applicable, Interventional, and Basic science
The aim of this study is to evaluate influence of atorvastin on the repolarisation phase of cardiomyocytes. If there is any, it could be a part of positive "non-lipid" effect of statins in therapy of ischaemic heart disease.
Study hypothesis: atorvastin will decrease heterogeneity of repolarisation of cardiomyocytes in comparison with placebo
The group will consist of 40 healthy volunteers. The study will be mono-centric. The repolarisation phase of cardiomyocytes will be evaluated using long - term 12-lead digital ECG monitoring. There will be 3 single ECG recordings - randomly after 20 mg of atorvastin, 80 mg of atorvastatin and placebo, respectively.
Masaryk University is the lead sponsor of 45 studies on the registry; 20 are open to participants now.
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atorvastatin 20 mg once vs. atorvastatin 80 mg once vs. placebo
No study locations are listed for this record.
This study is status unknown, as verified in Aug 2007. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Atorvastatin
Masaryk University