CClinicalTrials.gg
CompletedNCT00498641Updated Jul 10, 2007

Anisometropia Amblyopia Improved by Perceptual Learning and Patching

A Phase 3 interventional study of computer program and patching in Anisometropic Amblypia, sponsored by Tri-Service General Hospital. Completed. Open to participants aged 3 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2007-07-10.

Sponsored by Tri-Service General Hospital · Phase 3, Interventional, and Treatment

Phase
Phase 3
Study type
Interventional
Allocation
Randomized
Ages
3 Years to 55 Years
Sex
All
01

Study summary

To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.

Read the detailed description

Patients with anisometropic amblyopia were randomized to patching or perceptual learning group. Corrected amblyopic logMAR visual acuity and contrast sensitivity function were measured at four-weekly intervals until visual acuity stabilized or amblyopia resolved. Improvement in visual acuity, contrast sensitivity, and the resolution of amblyopia were compared between groups.

02

Conditions studied

  • Anisometropic Amblypia

Keywords

  • perceptual learning
  • occlusion therapy
03

In context

Lead sponsor

Tri-Service General Hospital is the lead sponsor of 109 studies on the registry; 11 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
3 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Anisometropia without strabismus
  • An interocular acuity difference of at least 0.2 logMAR in children (3-7 years of age) or in older children and adult patients without a history of patching or atropine penalization
  • All patients wore their spectacle at least one year

Exclusion criteria

Exclusion Criteria:

  • A history of prior spectacle correction
  • A history of patching or optical penalization
  • The existence of an ocular disease that could contribute to decreased visual acuity
  • Learning difficulties
  • The presence of strabismus
05

Study design

Phase
Phase 3
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single

Interventions

  • Procedurecomputer program and patching
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What researchers measure

Primary outcomes

  1. Corrected amblyopic logMAR visual acuity and contrast sensitivity function

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 10, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00498641
Lead sponsor
Tri-Service General Hospital
First posted
Jul 10, 2007
Start date
Jan 2005
Completion
Jan 2007
Last update
Jul 10, 2007

Study contacts

Po Chen, MD
study director · Tri-Service General Hospital

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2007. You cannot join it, but the record below documents what was studied.

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