A Phase 1 interventional study of LY2405319 and Placebo in Type 2 Diabetes, sponsored by Eli Lilly and Company. Completed at 11 sites in 4 countries. Open to participants aged 35 Years to 70 Years. Per ClinicalTrials.gov, last updated 2010-09-13.
Sponsored by Eli Lilly and Company · Phase 1, Interventional, and Treatment
This study intends to evaluate how safe and well tolerated the LY2405319 compound is when given to people for 7 days (in Part 1) and 28 days (in Part 2). This study intends to also determine if there is a positive effect on lowering the level of glucose in people with type 2 diabetes.
Subjects in Part 1 will be randomized to receive LY2405319 or placebo over 7 days in one of 4 dose level groups, in ascending order: 1 mg, 3 mg, 10 mg, or 20 mg.
Subjects in Part 2 will be randomized to receive LY2405319 or placebo over 28 days, and will receive the dose level determined to be the most well tolerated in Part 1.
10,925 studies on the registry are indexed under Diabetes Mellitus; 1,319 are open to participants now.
This study's enrollment of 37 is below the median of 80 across 8,367 interventional studies indexed under Diabetes Mellitus.
Browse Diabetes Mellitus studies →Eli Lilly and Company is the lead sponsor of 2,048 studies on the registry; 140 are open to participants now.
Of its 521 completed or terminated interventional studies of FDA-regulated products, 341 (65%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Safety labs, ECGs, vital signs, adverse events.
Time frame: End of dosing period
Pharmacodynamics (lab samples) and Pharmacokinetics (lab samples)
Time frame: End of dosing period
This study is completed, as verified in Sep 2010. You cannot join it, but the record below documents what was studied.
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Eli Lilly and Company