A Phase 2 interventional study of TD-1792 and Vancomycin in Staphylococcal Skin Infection, sponsored by Theravance Biopharma. Completed at 1 site in United States. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2021-01-20.
Sponsored by Theravance Biopharma (part of Zymeworks) · Phase 2, Interventional, and Treatment
The purpose of this study is to determine whether TD-1792 is safe and effective when used to treat complicated skin and skin structure infections caused by Gram-positive bacteria.
TD-1792 is compared to vancomycin for the treatment of cSSSI.
30 studies on the registry are indexed under Staphylococcal Skin Infections; none are open to participants now.
This study's enrollment of 203 is below the median of 227 across 28 interventional studies indexed under Staphylococcal Skin Infections.
Browse Staphylococcal Skin Infections studies →Theravance Biopharma is the lead sponsor of 47 studies on the registry; none are open to participants now.
Of its 24 completed or terminated interventional studies of FDA-regulated products, 11 (46%) have results posted.
First submitted before Theravance Biopharma became part of Zymeworks.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
On an ECG, the QT interval is the time the heart’s lower chambers take to activate electrically and recover in each beat. QTc is that time adjusted for heart rate (QTcF by Fridericia’s formula, QTcB by Bazett’s). Some medicines lengthen it, and a long QTc can raise the risk of a dangerous heart rhythm.
The study may name a correction formula and a limit in milliseconds, often around 450–480.
QT and QTc
On an ECG, the QT interval is the time the heart’s lower chambers take to activate electrically and recover in each beat. QTc is that time adjusted for heart rate (QTcF by Fridericia’s formula, QTcB by Bazett’s). Some medicines lengthen it, and a long QTc can raise the risk of a dangerous heart rhythm.
The study may name a correction formula and a limit in milliseconds, often around 450–480.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Drug: TD-1792
Drug: Vancomycin
TD-1792 2 mg/kg/day IV
Vancomycin 1 Gm IV q 12 hrs
Clinical response
Time frame: 7 to 14 days after last antibiotic dose
This study is completed, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.
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Staphylococcal Skin Infections →