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CompletedNCT00434395Updated Nov 25, 2019

Study Evaluating the Effects of MOA-728 on Cardiac Repolarization in Healthy Subjects

A Phase 1 interventional study of MOA-728 in Healthy, sponsored by Bausch Health Americas, Inc.. Completed at 1 site in United States. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-11-25.

Sponsored by Bausch Health Americas, Inc. · Phase 1, Interventional, and Treatment

Phase
Phase 1
Study type
Interventional
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
All
01

Study summary

The purpose of the study is to assess the effects of MOA-728 on cardiac repolarization in healthy subjects.

02

Conditions studied

  • Healthy
03

In context

Lead sponsor

Bausch Health Americas, Inc. is the lead sponsor of 209 studies on the registry; 9 are open to participants now.

Of its 23 completed or terminated interventional studies of FDA-regulated products, 16 (70%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Generally healthy subjects men or women aged 18-50

Exclusion criteria

Exclusion Criteria:

  • Any significant clinically important disease
  • Family history of long QT syndrome and/or sudden cardiac death
  • Allergy to moxifloxacin or the quinolone class of antibiotics
05

Study design

Phase
Phase 1
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Double

Interventions

  • DrugMOA-728
06

What researchers measure

Primary outcomes

  1. Cardiac repolarization will be assessed by the QTc interval in healthy subjects.

07

Study locations

1 site
  • Phoenix, Arizona 85044, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 25, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00434395
Lead sponsor
Bausch Health Americas, Inc.
First posted
Feb 13, 2007
Start date
Mar 2007
Completion
Oct 2007
Last update
Nov 25, 2019

Study contacts

Jeff Cohn
study director · Bausch Health Americas, Inc.
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2019. You cannot join it, but the record below documents what was studied.

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