An observational study in Enterovirus Infections, sponsored by Insel Gruppe AG, University Hospital Bern. Completed at 1 site in Switzerland. Open to participants aged Up to 16 Years. Per ClinicalTrials.gov, last updated 2011-05-19.
Sponsored by Insel Gruppe AG, University Hospital Bern · Observational
Enteroviruses can infect most human organ systems, especially the heart, nervous system and pancreas. Whether Enteroviruses can also affect the kidneys is not known yet. Therefore we will analyze urine of children with a suspected enteroviral infection for enteroviruses and signs of kidney infection.
Enteroviruses have been shown to cause mesangioproliferation and glomerulonephritis in mice (especially coxsackievirus B4). In some cases, large amounts of IgA are deposited in the mesangium, resembling human IgA-nephropathy. In humans, case reports indicate the propensity of certain enteroviruses to cause kidney infections.
Our project aims to analyze urine of children with suspected enteroviral infections (e.g. meningitis, myocarditis, sepsis of the newborn etc.) to identify cases suspicious of concomitant enteroviral kidney affection. To achieve this aim, enterovirus-PCRs will be performed and microhematuria searched for.
6,687 studies on the registry are indexed under Infections; 807 are open to participants now.
This study's enrollment of 82 is below the median of 240 across 2,136 observational studies indexed under Infections.
Browse Infections studies →Insel Gruppe AG, University Hospital Bern is the lead sponsor of 724 studies on the registry; 177 are open to participants now.
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children age 0-16
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This study is completed, as verified in May 2011. You cannot join it, but the record below documents what was studied.
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Insel Gruppe AG, University Hospital Bern