CClinicalTrials.gg
CompletedNCT00414622Updated Apr 19, 2007

GTS21-201 for Alzheimer Disease:GTS-21 Administered Daily for 28 Days to Participants With Probable Alzheimer's Disease

A Phase 2 interventional study of DMXB-A in Alzheimer Disease, sponsored by CoMentis. Completed at 1 site in United States. Open to participants aged 50 Years to 80 Years. Per ClinicalTrials.gov, last updated 2007-04-19.

Sponsored by CoMentis · Phase 2, Interventional, and Treatment

Phase
Phase 2
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
50 Years to 80 Years
Sex
All
01

Study summary

A Double Blind, Placebo-Controlled Randomized Study to Compare the Safety and Tolerability of GTS-21 (25 Mg TID, 50 Mg TID, 75 Mg TID and 150 Mg TID) When Administered Daily for 28 Days to Participants With Probable Alzheimer's Disease

Read the detailed description

A Double Blind, Placebo-Controlled Randomized Study to Compare the Safety and Tolerability of GTS-21 (25 Mg TID, 50 Mg TID, 75 Mg TID and 150 Mg TID) When Administered Daily for 28 Days to Participants With Probable Alzheimer's Disease

02

Conditions studied

  • Alzheimer Disease

Browse trials for

Keywords

  • Alzheimer
  • Probable Alzheimer disease
03

In context

Alzheimer Disease

3,678 studies on the registry are indexed under Alzheimer Disease; 872 are open to participants now.

This study's enrollment of 60 is below the median of 70 across 2,808 interventional studies indexed under Alzheimer Disease.

Browse Alzheimer Disease studies →

Lead sponsor

CoMentis is the lead sponsor of 9 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • probable Alzheimer

Exclusion criteria

Exclusion Criteria:

  • others
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
60 participants

Interventions

  • DrugDMXB-A
06

What researchers measure

Primary outcomes

  1. CDR

Secondary outcomes

  1. ADAS-cog

07

Study locations

1 site
  • Clinical Dept.
    280 South San Francisco, California, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 19, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00414622
Lead sponsor
CoMentis
First posted
Dec 21, 2006
Start date
Nov 2006
Completion
Apr 2007
Last update
Apr 19, 2007

Study contacts

Henry Hsu, MD
study director · CoMentis
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2006. You cannot join it, but the record below documents what was studied.

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