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WithdrawnNCT00363753Updated Aug 2, 2019

Pilot Study of Continuing Aspirin Versus Switching to Clopidogrel After Stroke or Transient Ischemic Attack

A Phase 1 interventional study of aspirin versus clopidogrel in Transient Ischemic Attack, Stroke and Aspirin, sponsored by University of California, San Diego. Withdrawn at 2 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-08-02.

Sponsored by University of California, San Diego · Phase 1, Interventional, and Prevention

Phase
Phase 1
Study type
Interventional
Enrollment
0
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Pilot study of continuing aspirin versus switching to clopidogrel after stroke or transient ischemic attack.

Read the detailed description

Pilot study of continuing aspirin versus switching to clopidogrel after stroke or transient ischemic attack.

02

Conditions studied

  • Transient Ischemic Attack
  • Stroke
  • Aspirin
  • Clopidogrel

Keywords

  • Transient ischemic attack
  • Stroke
  • Aspirin
  • Clopidogrel
03

In context

Stroke

7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.

Browse Stroke studies →

Lead sponsor

University of California, San Diego is the lead sponsor of 958 studies on the registry; 191 are open to participants now.

Of its 110 completed or terminated interventional studies of FDA-regulated products, 70 (64%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age 18 and older.
  • Stroke or transient ischemic attack (TIA) while taking aspirin within one week of consent.
  • Women of child-bearing potential will be included only if there is a negative pregnancy test and they agree to birth control during the treatment period.

Exclusion criteria

Exclusion Criteria:

  • Any medical indication for a specific antiplatelet agent (aspirin, clopidogrel, ticlopidine, aggrenox), or an indication for a combination of antiplatelet agents.
  • Any medical indication for anticoagulation, except subcutaneous heparin for deep vein thrombosis prophylaxis.
  • Allergy to aspirin or clopidogrel.
05

Study design

Phase
Phase 1
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
0 participants (actual)

Interventions

  • Drugaspirin versus clopidogrel
06

What researchers measure

Primary outcomes

  1. mRS at three months.

Secondary outcomes

  1. Incidence of stroke at three months, bleeding events.

07

Study locations

2 sites
  • UCSD Hillcrest
    San Diego, California 92103, United States
  • UCSD
    San Diego, California 92103, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 2, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00363753
Lead sponsor
University of California, San Diego
First posted
Aug 15, 2006
Start date
Aug 2006
Completion
Mar 2007 (estimated)
Last update
Aug 2, 2019

Study contacts

Matt B Jensen, MD
principal investigator · UCSD Stroke Center
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Jul 2019. You cannot join it, but the record below documents what was studied.

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