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CompletedNCT00346866Updated Aug 5, 2008

Anecortave Acetate Versus Placebo in AMD Patients Following PDT

A Phase 2 interventional study of anecortave acetate in AMD, sponsored by Alcon Research. Completed at 1 site in United States. Open to participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2008-08-05.

Sponsored by Alcon Research · Phase 2, Interventional, and Treatment

Phase
Phase 2
Study type
Interventional
Enrollment
136
Allocation
Randomized
Ages
50 Years and older
Sex
All
01

Study summary

The purpose of this study was to evaluate the efficacy of anecortave acetate for depot suspension (30 mg and 15 mg) plus PDT versus PDT alone with respect to maintenance of visual acuity in patients with wet AMD.

02

Conditions studied

  • AMD
03

In context

Lead sponsor

Alcon Research is the lead sponsor of 608 studies on the registry; 9 are open to participants now.

Of its 109 completed or terminated interventional studies of FDA-regulated products, 99 (91%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • AMD disease

Exclusion criteria

Exclusion Criteria:

  • Age
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
136 participants

Interventions

  • Druganecortave acetate
06

What researchers measure

Primary outcomes

  1. Mean change from the baseline in logMAR visual acuity score at Month 6

Secondary outcomes

  1. % patients who maintained vision, number of months of angiographic evidence of needing PDT re-treatment, and mean lesion sizes for the total choroidal neovascularization (CNV) and the classic component to the total CNV.

07

Study locations

1 site
  • Facility
    Beachwood, Ohio 44122, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 5, 2008, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00346866
Lead sponsor
Alcon Research
First posted
Jun 30, 2006
Start date
May 2000
Primary completion
Dec 2001
Completion
Dec 2001
Last update
Aug 5, 2008

Study contacts

Patricia Zilliox
study director · Alcon Research
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2008. You cannot join it, but the record below documents what was studied.

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