A Phase 3 interventional study of Moxifloxacin and Povidone Iodine vs Povidone Iodine in Eye Infections, sponsored by HaEmek Medical Center, Israel. Status unknown at 1 site in Israel. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2007-06-01.
Sponsored by HaEmek Medical Center, Israel · Phase 3, Interventional, and Prevention
The hypothesis is that povidone iodine alone is sufficient for sterilization of the lacrimal sac and eye lids before intraocular surgeries. Patients admitted for various intraocular surgeries will be randomly allocated to prophylactic local therapy with either moxifloxacin and povidone iodine or povidone iodine alone before surgery. Lacrimal sac and eye lid cultures will be obtained before the local therapy and just before surgery.
Over all 500 patients admitted for various intraocular surgeries will be included in the study. The study will be prospective, double blind, placebo controlled, and randomized. Patients will be randomly allocated to prophylactic local therapy with either moxifloxacin and povidone iodine or povidone iodine alone before surgery. For patients treated with povidone iodine alone a placebo will also be given. Lacrimal sac and eye lid cultures will be obtained before the local therapy and just before surgery. All patients will be followed for 6 weeks for symptoms and signs of infection. Bacterial and fungal culture results will be compared between the 2 groups.
35 studies on the registry are indexed under Eye Infections; 4 are open to participants now.
This study's planned enrollment of 500 is above the median of 120 across 22 interventional studies indexed under Eye Infections.
Browse Eye Infections studies →HaEmek Medical Center, Israel is the lead sponsor of 237 studies on the registry; 11 are open to participants now.
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Exclusion Criteria:
Type and amount of bacterial growth
Post surgery infections
This study is status unknown, as verified in Mar 2007. You cannot join it, but the record below documents what was studied.
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HaEmek Medical Center, Israel →