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CompletedNCT00273793Updated Jun 21, 2012Results posted

Increasing Contingency Management Success in Smoking Cessation

An interventional study of Contingency Management in Smoking, sponsored by The University of Texas Health Science Center at San Antonio. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2012-06-21.

Sponsored by The University of Texas Health Science Center at San Antonio · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
328
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Incentives can be used to facilitate the acquisition of many healthy behaviors, such as smoking cessation. However, there is much room for improvement in the use of incentives. This study investigates how two aspects of providing incentives influence the effectiveness of using incentives to promote smoking cessation. One aspect is the criterion for providing incentives, e.g., whether to require smoking cessation before providing an incentive or to provide incentives following smoking reductions. The other aspect being investigated is whether it is best to use a fixed incentive amount or an amount that increases with continued cessation success.

02

Conditions studied

  • Smoking
03

In context

Lead sponsor

The University of Texas Health Science Center at San Antonio is the lead sponsor of 435 studies on the registry; 88 are open to participants now.

Of its 62 completed or terminated interventional studies of FDA-regulated products, 31 (50%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Eligibility criteria

Inclusion Criteria: Daily Smokers smoking a pack or more of cigarettes a day who are able to report to the study site each work day for about 5 minutes for around 3 months. Subjects must also have a breath CO level indicative of smoking at this level, and most report smoking for at least two years. Subjects must intend on quitting smoking.

-

Exclusion Criteria: Participation in another study by this group within the past year. Inability to give informed consent. Incapable of attendance each workday during the morning hours.

-

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
328 participants (actual)

Study arms

  • Experimental
    1

    Shaping intervention for hard-to-treat smokers

    Behavioral: Contingency Management

  • Active comparator
    2

    fixed criterion intervention for hard-to-treat smokers

    Behavioral: Contingency Management

  • Other
    3

    Non contingent incentives available to hard to treat smokers

    Behavioral: Contingency Management

  • Experimental
    4

    Ascending incentives values used in Smokers with Early Success

    Behavioral: Contingency Management

  • Active comparator
    5

    fixed value incentives are used in Smokers with Early Success

    Behavioral: Contingency Management

  • Other
    6

    Non contingent incentives are available to Smokers with Early Success

    Behavioral: Contingency Management

Interventions

  • BehavioralContingency Management

    incentives are available for reduced smoking on each study visit which occur each weekday.

06

What researchers measure

Primary outcomes

  1. Breath Carbon Monoxide Levels Indicating Smoking Abstinence During the Study, i.e., the Number of Breath Samples With Carbon Monoxide (CO) Levels Less Than 3 Parts Per Million (Ppm)

    Time frame: daily for breath CO

Secondary outcomes

  1. Average Number Cigarettes Reported Smoked Each Day in the Past Week Measured at Follow-up Six Months After Entry Into the Study

    average number cigarettes reported smoked each day in the past week at follow up six months after study entry

    Time frame: past week at follow-up six months after study entry

07

Results

Posted Jun 7, 2012
Limitations and caveats
The study was conducted largely as planned. However the study was not designed to adequately test post-treatment outcomes, as this would not be justifiable unless during treatment differences were observed.

Participant flow

Individuals smoking at least 15 cigarettes per day that are at least 18 years old, and deliver a breath CO level greater than or equal to 15 ppm were recruited in a University setting from the general community.

Participant flow — Overall Study
MilestoneShaping Intervention for Hard-to-treat SmokersFixed Criterion Intervention for Hard-to-treat SmokersNon Contingent Incentives Available to Hard to Treat SmokersAscending Incentives Values Used in Smokers With Early SuccessFixed Value Incentives Are Used in Smokers With Early SuccessNon Contingent Incentives Are Available to Smokers With Early
Started363818605829
Completed363818605829
Not completed000000

Outcome measures

PrimaryBreath Carbon Monoxide Levels Indicating Smoking Abstinence During the Study, i.e., the Number of Breath Samples With Carbon Monoxide (CO) Levels Less Than 3 Parts Per Million (Ppm)
Time frame:
daily for breath CO
Reported as:
Median · number breath samples < 3 ppm CO
Breath Carbon Monoxide Levels Indicating Smoking Abstinence During the Study, i.e., the Number of Breath Samples With Carbon Monoxide (CO) Levels Less Than 3 Parts Per Million (Ppm)
number breath samples < 3 ppm COShaping Intervention for Hard-to-Treat SmokersFixed Criterion Intervention for Hard-to-Treat SmokersNon Contingent Incentives Available to Hard-to-Treat SmokersAscending Incentive Values Used in Smokers With Early SuccessFixed Value Incentives Are Used in Smokers With Early SuccessNon Contingent Incentives Are Available to Smokers With Early
Breath Carbon Monoxide Levels Indicating Smoking Abstinence During the Study, i.e., the Number of Breath Samples With Carbon Monoxide (CO) Levels Less Than 3 Parts Per Million (Ppm)2 (0 to 12.5)3.5 (0 to 39)0 (0 to 12.0)58.5 (15 to 64)49.5 (25 to 61)28 (6 to 59)
SecondaryAverage Number Cigarettes Reported Smoked Each Day in the Past Week Measured at Follow-up Six Months After Entry Into the Study

average number cigarettes reported smoked each day in the past week at follow up six months after study entry

Time frame:
past week at follow-up six months after study entry
Reported as:
Mean · cigarettes per day
Average Number Cigarettes Reported Smoked Each Day in the Past Week Measured at Follow-up Six Months After Entry Into the Study
cigarettes per dayShaping Intervention for Hard-to-Treat SmokersFixed Criterion Intervention for Hard-to-Treat SmokersNon Contingent Incentives Available to Hard-to-Treat SmokersAscending Incentive Values Used in Smokers With Early SuccessFixed Value Incentives Are Used in Smokers With Early SuccessNon Contingent Incentives Are Available to Smokers With Early
Average Number Cigarettes Reported Smoked Each Day in the Past Week Measured at Follow-up Six Months After Entry Into the Study12.8 ± 12.012.6 ± 7.715.1 ± 8.211.5 ± 9.911.1 ± 8.28.2 ± 7.2

Adverse events

Non-serious events are listed at a 1% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Shaping Intervention for Hard-to-treat Smokers—0/36 (0%)0/36 (0%)
Fixed Criterion Intervention for Hard-to-treat Smokers—0/38 (0%)0/38 (0%)
Non Contingent Incentives Available to Hard to Treat Smokers—0/18 (0%)0/18 (0%)
Ascending Incentives Values Used in Smokers With Early Success—0/60 (0%)0/60 (0%)
Fixed Value Incentives Are Used in Smokers With Early Success—0/58 (0%)0/58 (0%)
Non Contingent Incentives Are Available to Smokers With Early—0/29 (0%)0/29 (0%)

Baseline characteristics

Age, Categorical
Age, Categorical(Participants)Shaping Intervention for Hard-to-treat SmokersFixed Criterion Intervention for Hard-to-treat SmokersNon Contingent Incentives Available to Hard to Treat SmokersAscending Incentives Values Used in Smokers With Early SuccessFixed Value Incentives Are Used in Smokers With Early SuccessNon Contingent Incentives Are Available to Smokers With EarlyTotal
<=18 years0000000
Between 18 and 65 years363718595829237
>=65 years0101002
Age Continuous
Age Continuous(years)Shaping Intervention for Hard-to-treat SmokersFixed Criterion Intervention for Hard-to-treat SmokersNon Contingent Incentives Available to Hard to Treat SmokersAscending Incentives Values Used in Smokers With Early SuccessFixed Value Incentives Are Used in Smokers With Early SuccessNon Contingent Incentives Are Available to Smokers With EarlyTotal
Mean44.8 ± 12.243.3 ± 12.843.1 ± 11.241.9 ± 12.941.3 ± 11.840.6 ± 10.042.5 ± 12.0
Sex: Female, Male
Sex: Female, Male(Participants)Shaping Intervention for Hard-to-treat SmokersFixed Criterion Intervention for Hard-to-treat SmokersNon Contingent Incentives Available to Hard to Treat SmokersAscending Incentives Values Used in Smokers With Early SuccessFixed Value Incentives Are Used in Smokers With Early SuccessNon Contingent Incentives Are Available to Smokers With EarlyTotal
Female1212725261698
Male242611353213141
Region of Enrollment
Region of Enrollment(participants)Shaping Intervention for Hard-to-treat SmokersFixed Criterion Intervention for Hard-to-treat SmokersNon Contingent Incentives Available to Hard to Treat SmokersAscending Incentives Values Used in Smokers With Early SuccessFixed Value Incentives Are Used in Smokers With Early SuccessNon Contingent Incentives Are Available to Smokers With EarlyTotal
United States363818605829239
08

Study locations

1 site
  • Smoking Cessation Laboratory, Department of Psychiatry, UTHSCSA, 7703 Floyd Curl Drive
    San Antonio, Texas 78229-3900, United States
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 21, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00273793
Lead sponsor
The University of Texas Health Science Center at San Antonio
Collaborators
National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH)
Responsible party
Sponsor
First posted
Jan 9, 2006
Start date
Jun 2005
Primary completion
Jun 2010
Completion
Nov 2010
Results posted
Jun 7, 2012
Last update
Jun 21, 2012

Study contacts

Richard J Lamb, Ph.D.
principal investigator · The University of Texas Health Science Center at San Antonio
View the source record on ClinicalTrials.gov ↗

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