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CompletedNCT00185055Updated Sep 16, 2005

The Relative Effects of Olmesartan Medoxomil, Irbesartan and Valsartan on the Activity of the Blood Pressure Control System in Healthy Subjects

A Phase 4 interventional study of Olmesartan medoxomil and Irbesartan in Healthy, sponsored by Daiichi Sankyo. Completed. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2005-09-16.

Sponsored by Daiichi Sankyo · Phase 4, Interventional, and Treatment

Phase
Phase 4
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years to 65 Years
Sex
All
01

Study summary

To assess the effects of 3 blood pressure drugs, called angiotensin receptor blockers, on the blood pressure control systems in healthy subjects.

02

Conditions studied

  • Healthy

Keywords

  • olmesartan
  • valsartan
  • irbesartan
  • renin-angiotensin-aldosterone system
03

In context

Lead sponsor

Daiichi Sankyo is the lead sponsor of 316 studies on the registry; 35 are open to participants now.

Of its 51 completed or terminated interventional studies of FDA-regulated products, 38 (75%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Men and women between the ages of 18 to 65
  • In good health

Exclusion criteria

Exclusion Criteria:

  • Any serious health problems
  • Positive test for HIV, Hepatitis B and C
  • History of drug and alcohol abuse
05

Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Single
Enrollment
20 participants

Interventions

  • DrugOlmesartan medoxomil
  • DrugIrbesartan
  • DrugValsartan
06

What researchers measure

Primary outcomes

  1. To characterize the plasma renin activity (PRA) and urinary aldosterone response patterns to single doses of olmesartan medoxomil, irbesartan, and valsartan compared to placebo in normal volunteers.

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 16, 2005, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00185055
Lead sponsor
Daiichi Sankyo
First posted
Sep 16, 2005
Start date
Nov 2004
Completion
Feb 2005
Last update
Sep 16, 2005
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2005. You cannot join it, but the record below documents what was studied.

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