CClinicalTrials.gg
Status unknownNCT00181012Updated Sep 19, 2007

Benefit of Lidocaine Perfusion in Cancer Related Visceral Pain Resistant to Morphinics

A Phase 3 interventional study of Lidocaine in Cancer and Pain, sponsored by Gustave Roussy, Cancer Campus, Grand Paris. Status unknown at 1 site in France. Open to participants aged 6 Years to 70 Years. Per ClinicalTrials.gov, last updated 2007-09-19.

Sponsored by Gustave Roussy, Cancer Campus, Grand Paris · Phase 3, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Sep 2006), so the status shown — last known as Recruiting — may be out of date.
Phase
Phase 3
Study type
Interventional
Enrollment
100
Allocation
Randomized
Ages
6 Years to 70 Years
Sex
All
01

Study summary

This study will evaluate the benefit of lidocaine perfusion in cancer related visceral pain resistant to morphinics. It is an efficacy study in adults and children and a randomized prospective study.

02

Conditions studied

  • Cancer
  • Pain

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Keywords

  • Cancer Related Visceral Pain Resistant to Morphinics
03

In context

Visceral Pain

46 studies on the registry are indexed under Visceral Pain; 16 are open to participants now.

This study's planned enrollment of 100 is above the median of 68 across 42 interventional studies indexed under Visceral Pain.

Browse Visceral Pain studies →

Lead sponsor

Gustave Roussy, Cancer Campus, Grand Paris is the lead sponsor of 242 studies on the registry; 65 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
6 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients suffering from cancer of any type, at any stage, hospitalized at the Institut Gustave Roussy
  • Aged from 6 to 14 years old (group A) and from 15 to 70 years old (adults)
  • Presenting visceral pain due to neurotoxic chemotherapy, due to the tumoral mass or to peritoneal carcinosis
  • Pain resistant to morphinic treatment

Exclusion criteria

Exclusion Criteria:

  • Cardiac troubles, clinical cardiac insufficiency, or history of myocardial infarction (MI) of less than 3 months
  • Neurological: non-controlled epilepsy, encephalopathy, or dementia
  • Severe hepatic insufficiency
  • Severe renal insufficiency
  • Respiratory insufficiency
  • Patients having surgery or in postoperative period
  • Known deficit in G6PD, alanine exposure, or sulphamide treatment
  • Porphyria
  • Weight > 80 kg
05

Study design

Phase
Phase 3
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
100 participants (estimated)

Interventions

  • DrugLidocaine
06

What researchers measure

Primary outcomes

  1. To determine prospectively the lidocaine efficacy in 2 types of patient populations with cancer (group A: children from 6 to 14 years old and group B: adults from 15 to 70 years old)

    Time frame: continuous intravenous perfusion for 6 days

Secondary outcomes

  1. To confirm the tolerance of the lidocaine

07

Study locations

1 of 1 sites recruiting
  • Institut Gustave-Roussy
    Villejuif, 94800, France
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 19, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00181012
Lead sponsor
Gustave Roussy, Cancer Campus, Grand Paris
First posted
Sep 16, 2005
Start date
May 2005
Last update
Sep 19, 2007

Study contacts

Philippe Poulain, MD
Contact
poulain@igr.fr
33 1 42 11 40 53
Philippe Poulain, MD
principal investigator · Gustave Roussy, Cancer Campus, Grand Paris
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2006. You cannot join it, but the record below documents what was studied.

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