An observational study in Radiation Tolerance, sponsored by University of Rochester. Terminated at 1 site in United States. Per ClinicalTrials.gov, last updated 2009-05-19.
Sponsored by University of Rochester · Observational
Irradiation of any tissue creates changes in that tissue. Ionizing radiation imparts charges to the tissue as it interacts with tissue components, changing the tissue structure. The specific type of modification also depends to some extent upon the type of tissue irradiated. It has been shown that it is possible to read the tooth enamel irradiation record using techniques such as electron paramagnetic resonance (EPR), or electron spin resonance (ESR).
It is proposed to examine radiation responses in approximately one hundred (100) human teeth. This would include teeth free of, as well as those containing, amalgam (silver) restorations. For the first group, teeth that have already been collected (pre-existing pathological specimens) would be used. These teeth were surgical/pathological discards collected without identifiers by the dental providers.
University of Rochester is the lead sponsor of 715 studies on the registry; 116 are open to participants now.
Of its 56 completed or terminated interventional studies of FDA-regulated products, 44 (79%) have results posted.
Counted across the registry records on this site, refreshed daily.
discarded pathological specimen(teeth)
Inclusion Criteria:
Treatment for Cancer using Radiation -dose will be the standard of Care for the type of Cancer being treated
This study is terminated, as verified in May 2009. You cannot join it, but the record below documents what was studied.
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University of Rochester